NEIL3 抗体
Our Local Distributor
北京 101111
Quick Overview for NEIL3 抗体 (ABIN6241838)
抗原
See all NEIL3 抗体适用
宿主
克隆类型
标记
应用范围
-
-
免疫原
- synthetic peptide
-
-
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (AA 2-187) antibody
NEIL3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (AA 292-320) antibodyNEIL3 适用: 人 WB 宿主: 兔 Polyclonal RB40413 unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) antibodyNEIL3 适用: 人 DB 宿主: 小鼠 Monoclonal 2627C1b unconjugated
anti-Nei Endonuclease VIII-Like 3 (NEIL3) (C-Term) antibodyNEIL3 适用: 人, 小鼠, 大鼠 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
储存条件
- 4 °C,-20 °C
-
-
- NEIL3 (Nei Endonuclease VIII-Like 3 (NEIL3))
-
别名
- NEIL3
-
背景
- DNA glycosylase which prefers single-stranded DNA (ssDNA), or partially ssDNA structures such as bubble and fork structures, to double-stranded DNA (dsDNA). In vitro, displays strong glycosylase activity towards the hydantoin lesions spiroiminodihydantoin (Sp) and guanidinohydantoin (Gh) in both ssDNA and dsDNA, also recognizes FapyA, FapyG, 5-OHU, 5-OHC, 5- OHMH, Tg and 8-oxoA lesions in ssDNA. No activity on 8-oxoG detected. Also shows weak DNA-(apurinic or apyrimidinic site) lyase activity. In vivo, appears to be the primary enzyme involved in removing Sp and Gh from ssDNA in neonatal tissues. Seems to be an important facilitator of cell proliferation in certain populations, for example neural stem/progenitor cells and tumor cells, suggesting a role in replication-associated DNA repair.
-
UniProt
- Q8TAT5
-
途径
- DNA Damage Repair
抗原
-
