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beta Catenin 抗体 (pSer33, pSer37)

Name: beta Catenin 抗体 (pSer33, pSer37)
SKU: ABIN6241068
Availability: OutOfStock

This anti-beta Catenin antibody is a 兔多克隆 antibody detecting beta Catenin in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.

Western blot analysis of extracts from S cells, untreated or treated with Calyculin A, (100nM, 30 min), using Phospho-beta-catenin (Ser33/37) Antibody. (beta Catenin 抗体 (pSer33, pSer37))

1 image

(1 reference)

产品编号 ABIN6241068

发货至: 中国

Quick Overview for beta Catenin 抗体 (pSer33, pSer37) (ABIN6241068)

抗原

See all beta Catenin (CATNB) 抗体

beta Catenin (CATNB) (Catenin, beta (CATNB))

适用

人

宿主

兔

克隆类型

多克隆

标记

This beta Catenin antibody is un-conjugated

应用范围

Western Blotting (WB)

克隆位点

RB42029

Discover our top product CATNB Primary Antibody

抗原表位
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28

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1
AA 19-41, pSer33, pSer37

预测反应

B, Zf, M, Rat, X

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This Phospho-beta-catenin (Ser33/37) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 19-41 amino acids from human beta-catenin .

亚型

Ig Fraction
anti-Catenin, beta (CATNB) (pSer33), (pSer37) antibody
CATNB 适用: 人, 小鼠, 大鼠 WB, FACS, ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Catenin, beta (CATNB) (AA 661-781) antibody
CATNB 适用: 人, 小鼠, 大鼠, Pig, 斑马鱼 WB, FACS, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Catenin, beta (CATNB) (C-Term) antibody
CATNB 适用: 人, 小鼠, 大鼠, 小鸡, Cow, 犬, Pig, 兔, 绵羊, 猴, Hamster, Avian, Cat, 驴, 山羊, 豚鼠, 马 WB, IF 宿主: 山羊 Polyclonal unconjugated

anti-Catenin, beta (CATNB) (C-Term) antibody
CATNB 适用: 人, 斑马鱼 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Catenin, beta (CATNB) (pSer33), (pSer37), (pThr41) antibody
CATNB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Catenin, beta (CATNB) (AA 439-675) antibody
CATNB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Catenin, beta (CATNB) (AA 439-675) antibody
CATNB 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C11 unconjugated

anti-Catenin, beta (CATNB) antibody
CATNB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 4A3H3 unconjugated

anti-Catenin, beta (CATNB) antibody
CATNB 适用: 人, 小鼠, Hamster WB, IP, ICC, ICFC 宿主: 小鼠 Monoclonal EM-22 unconjugated

anti-Catenin, beta (CATNB) (AA 764-781) antibody
CATNB 适用: 人, 小鼠, 大鼠 WB, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:1000

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

有效期

6 months
Zhuang, Wang, Wang, Ma, Han, Zou, Wu, Dong, Qu, Zang, Wu: "MicroRNA-23b functions as an oncogene and activates AKT/GSK3β/β-catenin signaling by targeting ST7L in hepatocellular carcinoma." in: Cell death & disease, Vol. 8, Issue 5, pp. e2804, (2018) (PubMed).
抗原

beta Catenin (CATNB) (Catenin, beta (CATNB))

别名

beta-catenin

背景

Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome. In the presence of Wnt ligand, CTNNB1 is not ubiquitinated and accumulates in the nucleus, where it acts as a coactivator for transcription factors of the TCF/LEF family, leading to activate Wnt responsive genes. Involved in the regulation of cell adhesion. Acts as a negative regulator of centrosome cohesion. Involved in the CDK2/PTPN6/CTNNB1/CEACAM1 pathway of insulin internalization. Blocks anoikis of malignant kidney and intestinal epithelial cells and promotes their anchorage-independent growth by down-regulating DAPK2. Disrupts PML function and PML-NB formation by inhibiting RANBP2-mediated sumoylation of PML (PubMed:< a href="http://www.uniprot.org/citations/17524503" target="_blank">17524503, PubMed:< a href="http://www.uniprot.org/citations/18077326" target="_blank">18077326, PubMed:< a href="http://www.uniprot.org/citations/18086858" target="_blank">18086858, PubMed:< a href="http://www.uniprot.org/citations/18957423" target="_blank">18957423, PubMed:< a href="http://www.uniprot.org/citations/21262353" target="_blank">21262353, PubMed:< a href="http://www.uniprot.org/citations/22647378" target="_blank">22647378, PubMed:< a href="http://www.uniprot.org/citations/22699938" target="_blank">22699938, PubMed:< a href="http://www.uniprot.org/citations/22155184" target="_blank">22155184). Promotes neurogenesis by maintaining sympathetic neuroblasts within the cell cycle (By similarity).

分子量

85497

UniProt

P35222

途径

Peptide Hormone Metabolism