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MAPK6 抗体 (pSer189)

This anti-MAPK6 antibody is a 兔 多克隆 antibody detecting MAPK6 in IHC (p). Suitable for 人. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN6241031
发货至: 中国

Quick Overview for MAPK6 抗体 (pSer189) (ABIN6241031)

抗原

See all MAPK6 抗体
MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

适用

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宿主

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克隆类型

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多克隆

标记

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This MAPK6 antibody is un-conjugated

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB5800
  • 抗原表位

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    pSer189

    预测反应

    C, M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This Phospho-ERK3-S189 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S189 of human ERK3.

    亚型

    Ig Fraction
  • 应用备注

    IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Wang, Kong, Lin, Li, Izumiya, Ding, Zhang, Hu, Yang, Gao, Lam, Li: "A versatile nanoplatform for synergistic combination therapy to treat human esophageal cancer." in: Acta pharmacologica Sinica, Vol. 38, Issue 6, pp. 931-942, (2018) (PubMed).

    Perander, Al-Mahdi, Jensen, Nunn, Kildalsen, Johansen, Gabrielsen, Keyse, Seternes: "Regulation of atypical MAP kinases ERK3 and ERK4 by the phosphatase DUSP2." in: Scientific reports, Vol. 7, pp. 43471, (2017) (PubMed).

    De la Mota-Peynado, Chernoff, Beeser: "Identification of the atypical MAPK Erk3 as a novel substrate for p21-activated kinase (Pak) activity." in: The Journal of biological chemistry, Vol. 286, Issue 15, pp. 13603-11, (2011) (PubMed).

    Purcell, Wilkins, York, Saba-El-Leil, Meloche, Robbins, Molkentin: "Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 35, pp. 14074-9, (2007) (PubMed).

    Sakai, Yamauchi, Kawano: "[Measurement of internal voids in impression material using a digital image analyzer. Part 1. Investigation of the measurement system of a digital image analyzer]." in: Nihon Hotetsu Shika Gakkai zasshi, Vol. 32, Issue 1, pp. 28-36, (1989) (PubMed).

  • 抗原

    MAPK6 (Mitogen-Activated Protein Kinase 6 (MAPK6))

    别名

    ERK3

    背景

    ERK3 is a member of the Ser/Thr protein kinase family, and is most closely related to mitogen-activated protein kinases (MAP kinases). MAP kinases also known as extracellular signal-regulated kinases (ERKs), are activated through protein phosphorylation cascades and act as integration points for multiple biochemical signals. This kinase is localized in the nucleus, and has been reported to be activated in fibroblasts upon treatment with serum or phorbol esters.

    分子量

    82681

    NCBI登录号

    NP_002739

    UniProt

    Q16659

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation, Hepatitis C
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