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H2AFX 抗体 (pSer139)

H2AFX 适用: 人, 小鼠 WB, ICC 宿主: 小鼠 Monoclonal unconjugated
产品编号 ABIN6241012
发货至: 中国
  • 抗原 See all H2AFX 抗体
    H2AFX (H2A Histone Family, Member X (H2AFX))
    抗原表位
    • 43
    • 27
    • 18
    • 11
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    pSer139
    适用
    • 183
    • 84
    • 60
    • 26
    • 26
    • 20
    • 17
    • 12
    • 9
    • 3
    • 2
    • 2
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    • 1
    人, 小鼠
    宿主
    • 163
    • 20
    • 2
    小鼠
    克隆类型
    • 128
    • 57
    单克隆
    标记
    • 121
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    This H2AFX antibody is un-conjugated
    应用范围
    • 146
    • 53
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    • 43
    • 37
    • 27
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    • 1
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    Western Blotting (WB), Immunocytochemistry (ICC)
    免疫原
    Recombinant Protein
    Top Product
    Discover our top product H2AFX Primary Antibody
  • 应用备注
    WB: 1:2000. ICC: 1:400
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    4 °C,-20 °C
  • 抗原
    H2AFX (H2A Histone Family, Member X (H2AFX))
    别名
    Histone H2A.X (H2AFX 产品)
    别名
    H2A.X antibody, H2A/X antibody, H2AX antibody, AW228881 antibody, H2ax antibody, Hist5-2ax antibody, gammaH2ax antibody, zgc:56329 antibody, h2a.x antibody, h2a/x antibody, h2ax antibody, RGD1566119 antibody, h2a antibody, h2afx antibody, H2A histone family member X antibody, H2A histone family, member X antibody, H2A histone family member X L homeolog antibody, histone cluster 1, H2ah antibody, histone cluster 2, H2ab S homeolog antibody, histone H2AX antibody, H2AFX antibody, H2afx antibody, h2afx antibody, h2afx.L antibody, HIST1H2AH antibody, hist2h2ab.S antibody, LOC100522201 antibody, LOC100720536 antibody
    背景
    Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. Required for checkpoint-mediated arrest of cell cycle progression in response to low doses of ionizing radiation and for efficient repair of DNA double strand breaks (DSBs) specifically when modified by C- terminal phosphorylation.
    UniProt
    P16104
    途径
    Telomere Maintenance, DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
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