CD1c 抗体 (APC)
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北京 101111
Quick Overview for CD1c 抗体 (APC) (ABIN6240833)
抗原
See all CD1c (CD1C) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD1c APC
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特异性
- The mouse monoclonal antibody L161 recognizes an extracellular epitope of CD1c, (R7), a 43 kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on cortical thymocytes (strongly), Langerhans cells, dendritic cells, B and some T cells.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with activated allophycocyanin (APC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- human thymocytes
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亚型
- IgG1 kappa
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anti-T-cell surface glycoprotein CD1c (CD1C) (AA 18-302) antibody
CD1C 适用: 人 ELISA, FACS, IHC 宿主: 小鼠 Monoclonal 3G1B3 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibodyCD1C 适用: 人 FACS, IHC, IP 宿主: 小鼠 Monoclonal L161 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibodyCD1C 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 1H9 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) (AA 18-300) antibodyCD1C 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibodyCD1C 适用: 人 ELISA, LMNX 宿主: 小鼠 Monoclonal OTI1F4 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) (AA 18-302) antibodyCD1C 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibodyCD1C 适用: 人, 小鼠, 大鼠, 犬, 猴 WB 宿主: 小鼠 Monoclonal 1E10 unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) antibody (PE)CD1C 适用: 人 FACS 宿主: 小鼠 Monoclonal L161 PE
anti-T-cell surface glycoprotein CD1c (CD1C) (AA 226-253) antibodyCD1C 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-T-cell surface glycoprotein CD1c (CD1C) (AA 77-185) antibodyCD1C 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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- CD1c (CD1C) (T-cell surface glycoprotein CD1c (CD1C))
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别名
- CD1c
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背景
- CD1c molecule,CD1c (also known as R7 or BDCA1) together with CD1a and b, belongs to group 1 of CD1 antigens. These non-classical MHC-like glycoproteins serve as antigen-presenting molecules for a subset of T cells that responds to specific lipids and glycolipids found in the cell walls of bacterial pathogens or self-glycolipid antigens such as gangliosides, and they have also roles in antiviral immunity. The trafficking routes of the particular CD1 types differ and correspond to their ability to bind and present different groups of antigens. CD1c is unique in its ability to present e.g. mycobacterial phosphoketides and polyisoprenoids. CD1c is the only CD1 isoform that has been shown to interact both with alpha/beta and gamma/delta T cells.,R7, BDCA1
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基因ID
- 911
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UniProt
- P29017
抗原
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