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Fibrillarin 抗体

Cited in 1 publication. The 兔 多克隆 anti-Fibrillarin antibody (ABIN3021516) specifically detects Fibrillarin in WB 和 IHC. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN3021516
发货至: 中国
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Quick Overview for Fibrillarin 抗体 (ABIN3021516)

抗原

See all Fibrillarin (FBL) 抗体
Fibrillarin (FBL)

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This Fibrillarin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 纯化方法

    Affinity purification

    免疫原

    Recombinant protein of human FBL

    亚型

    IgG
  • 应用备注

    Recommended dilutions: WB: 1:500-1:2000, IHC: 1:50-1:200

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid freeze / thaw cycles

    储存条件

    -20 °C/-80 °C
  • Zheng, Xiong, Wu, Chen, Chen, Fleming, Gao, Bi, Ge: "Quantitative Proteomics Analysis Reveals Novel Insights into Mechanisms of Action of Long Noncoding RNA Hox Transcript Antisense Intergenic RNA (HOTAIR) in HeLa Cells." in: Molecular & cellular proteomics : MCP, Vol. 14, Issue 6, pp. 1447-63, (2015) (PubMed).

  • 抗原

    Fibrillarin (FBL)

    别名

    FBL

    背景

    Fibrillarin is a 2-O-methyltransferase located in fibrillar regions and Cajal bodies of the nucleolus, where RNA transcription and pre-RNA processing take place. Fibrillarin associates with several other structual proteins as well as box C/D snoRNA to form a complex that functions in pre-rRNA processing, pre-rRNA methylation and ribosome assembly. This complex catalyzes site-specific 2-O-ribose methylation of targeted nucleotides within the rRNA sequence. The sequence, structure and function of fibrillarin are highly conserved and fibrillarin gene expression is essential for early embryonic development.
    Synonyms: FBL, FIB, FLRN, RNU3IP1

    基因ID

    2091

    UniProt

    P22087

    途径

    Ribonucleoside Biosynthetic Process
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