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FTL 抗体 (AA 38-165) (CF®647)

This anti-FTL antibody is a 小鼠 单克隆 antibody detecting FTL in IHC, IF 和 FACS. Suitable for 人.
产品编号 ABIN6191672
发货至: 中国

Quick Overview for FTL 抗体 (AA 38-165) (CF®647) (ABIN6191672)

抗原

See all FTL 抗体
FTL (Ferritin, Light Polypeptide (FTL))

适用

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宿主

  • 88
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  • 2
小鼠

克隆类型

  • 105
  • 72
单克隆

标记

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This FTL antibody is conjugated to CF®647

应用范围

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Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

FTL-1389
  • 抗原表位

    • 73
    • 16
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    AA 38-165

    原理

    Mouse Monoclonal anti-Ferritin, Light chain (FTL/1389), CF647 Conjugate

    产品特性

    Mammalian ferritins consist of 24 subunits made up of 2 types of polypeptide chains, ferritin heavy chain and ferritin light chain. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human FTL protein fragment (aa 38-165) (exact sequence is proprietary)

    亚型

    IgG1
  • 应用备注

    Immunohistology (formalin) 0.1-0.2 μg/mL
    • Flow cytometry 0.1-0.2 μg/million cells Immunofluorescence 0.1-0.2 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
    • Optimal dilution for a specific application should be determined by user

    说明

    HepG2, HeLa, HL-60 or 293T cells. Pancreas, Liver, Cerebellum or Testis.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    FTL (Ferritin, Light Polypeptide (FTL))

    别名

    Ferritin, Light chain

    背景

    Ferritin L chain, Ferritin L subunit, Ferritin light chain, Ferritin light polypeptide, FTL, LFTD, NBIA3

    分子量

    19-25 kDa

    基因ID

    2512, 433670

    UniProt

    P02792

    途径

    Transition Metal Ion Homeostasis
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