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Recombinant CA 19-9 抗体 (CF®594)

This anti-CA 19-9 antibody is a 兔 单克隆 antibody detecting CA 19-9 in IHC, FACS 和 IF. Suitable for 人.
产品编号 ABIN6190548
发货至: 中国

Quick Overview for Recombinant CA 19-9 抗体 (CF®594) (ABIN6190548)

抗原

See all CA 19-9 抗体
CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

抗体类型

Recombinant Antibody

适用

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宿主

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克隆类型

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单克隆

标记

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This CA 19-9 antibody is conjugated to CF®594

应用范围

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Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

CA19-9-1390R
  • 原理

    Recombinant Rabbit Monoclonal anti-CA19-9/Sialyl-Lewisa (CA19.9/1390R), CF594 Conjugate

    产品特性

    CA19-9, a carbohydrate epitope expressed on a high MW (>400 kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Purified human CA19-9 protein

    亚型

    IgG kappa
  • 应用备注

    Immunofluorescence 0.5-1 μg/mL Immunohistology (formalin) 5-10 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer  pH 6.0for 10-20 min followed by cooling at RT for 20 min
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user

    说明

    Stomach or Colon Carcinoma

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))

    别名

    CA19-9/Sialyl-Lewisa

    背景

    CA19.9, Ovarian tumor antigen, Pancreatic tumor antigen, Sialyl Lewis a

    分子量

    >400 kDa
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