CA 19-9 抗体
Quick Overview for CA 19-9 抗体 (ABIN6190523)
抗原
See all CA 19-9 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-CA19-9 (Sialyl-Lewis-A) (121SLE), Purified, BSA-free
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产品特性
- CA19-9, a carbohydrate epitope expressed on a high MW (>400 kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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纯化方法
- Purified
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免疫原
- Precipitin lines obtained after immuno-diffusion using MAb 116-NS-19-9 and mucins isolated from an ovarian cyst of a Lewis A B- patient (0Le).
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亚型
- IgM kappa
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anti-Gastrointestinal Cancer Antigen CA19-9 (CA 19-9) antibody
CA 19-9 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 121SLE unconjugated
anti-Gastrointestinal Cancer Antigen CA19-9 (CA 19-9) antibodyCA 19-9 适用: 人 ELISA, FACS, IHC (p), WB, IHC (fro) 宿主: 小鼠 Monoclonal 121SLE unconjugated
anti-Gastrointestinal Cancer Antigen CA19-9 (CA 19-9) antibodyCA 19-9 适用: 人 IHC, StM 宿主: 兔 Monoclonal CA19-9-1390R unconjugated
anti-Gastrointestinal Cancer Antigen CA19-9 (CA 19-9) antibodyCA 19-9 适用: 人 IHC, FACS, IF, ISt 宿主: 小鼠 Monoclonal SPM588 unconjugated
anti-Gastrointestinal Cancer Antigen CA19-9 (CA 19-9) antibodyCA 19-9 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal 121SLE unconjugated
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应用备注
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Immunohistology (formalin)
- No special pretreatment is required for the immunohistochemical staining of formalin-fixed, paraffin-embedded tissues
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
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说明
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Stomach or Colon Carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS (no BSA, no azide)
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储存液
- Azide free
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- CA 19-9 (Gastrointestinal Cancer Antigen CA19-9 (CA 19-9))
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别名
- CA19-9 (Sialyl-Lewis-A)
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背景
- CA19.9, Ovarian tumor antigen, Pancreatic tumor antigen, Sialyl Lewis a
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分子量
- >400 kDa
抗原
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