PLGF 抗体 (CF®568)
Quick Overview for PLGF 抗体 (CF®568) (ABIN6189208)
抗原
See all PLGF (PGF) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-PLGF (PLGF/93), CF568 Conjugate
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产品特性
- The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include Fibroblast Growth Factor (FGF), Platelet Derived Growth Factor (PDGF), Vascular Endothelial Growth Factor (VEGF) and Placenta Growth Factor (PLGF). Placenta growth factor (PLGF) is a secreted protein primarily produced by placental trophoblasts but also expressed in other endothelial cells and tumors. There are three isoforms, PLGF-1, PLGF-2, and PLGF-3. PLGF-2 is expressed up until week 8 in the placenta, the placental tissues continuously express PLGF-1 and PLGF-3 but only PLGF-1 is found in colon and mammary carcinomas. PLGF acts to stimulate angiogenesis, endothelial growth and migration. PLGF is a powerful promoter of tumor growth and is upregulated in some cancers, and PLGF is thought to aid in atherosclerotic lesions and neovascular growth surrounding the lesion. Also, PLGF appears to aid aldosterone mediated atherosclerosis. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human PLGF protein
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亚型
- IgG1 kappa
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anti-Placenta Growth Factor (PGF) (Internal Region) antibody
PGF 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) (AA 166-221) antibodyPGF 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) (AA 19-170) antibodyPGF 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) (AA 101-158) antibodyPGF 适用: 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) (AA 43-162) antibodyPGF 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) (AA 24-158) antibodyPGF 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) antibodyPGF 适用: 人 ELISA, IHC 宿主: 兔 Monoclonal 1B6 unconjugated Recombinant Antibody
anti-Placenta Growth Factor (PGF) (AA 1-170) antibodyPGF 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) (AA 1-170) antibodyPGF 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Placenta Growth Factor (PGF) (AA 131-158) antibodyPGF 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- ELISA For coating, order Ab without BSA
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说明
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HepG2 or HEK293T cells. Human placental and brain tumors.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- PLGF (PGF) (Placenta Growth Factor (PGF))
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别名
- PLGF
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背景
- PGFL, PIGF, placental growth factor (PGF), Vascular endothelial growth factor related protein
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分子量
- 18 kDa
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基因ID
- 5228, 252820
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UniProt
- P49763
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途径
- VEGFR1 Specific Signals
抗原
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