CD33 抗体 (CF®640R)
Quick Overview for CD33 抗体 (CF®640R) (ABIN6181294)
抗原
See all CD33 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-CD33 (C33/68), CF640R Conjugate
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产品特性
- This antibody recognizes a 67 kDa glycoprotein, which is identified as CD33. It is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies, these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. CD33 is expressed on myeloid progenitors, monocytes, granulocytes, dendritic cells and mast cells. It is absent on platelets, lymphocytes, erythrocytes and hematopoietic stem cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human CD33 protein
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亚型
- IgG1 kappa
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anti-CD33 (CD33) (AA 101-200) antibody
CD33 适用: 人, 小鼠 FACS, WB, ELISA, IHC (fro), ICC, IF (p), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD33 (CD33) (AA 15-237) antibodyCD33 适用: 人 FACS, WB, ELISA, IHC 宿主: 小鼠 Monoclonal 2C6B7 unconjugated
anti-CD33 (CD33) (AA 15-237) antibodyCD33 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 2C6B7 unconjugated
anti-CD33 (CD33) (AA 18-240) antibodyCD33 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD33 (CD33) (AA 49-259) antibodyCD33 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD33 (CD33) (AA 261-364) antibodyCD33 适用: 人 FACS, WB, ELISA, IHC (fro), IF (p), IF (cc), IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD33 (CD33) (AA 1-364) antibodyCD33 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2D12-G4 unconjugated
anti-CD33 (CD33) antibodyCD33 适用: 人, 小鼠, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD33 (CD33) antibodyCD33 适用: 人, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, Func, MS 宿主: 小鼠 Monoclonal WM53 unconjugated
anti-CD33 (CD33) antibodyCD33 适用: 人, Non-Human Primate FACS, WB, IP, IHC (fro), ICC, MS 宿主: 小鼠 Monoclonal WM53 unconjugated
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应用备注
- Immunofluorescence 0.5-1 μg/mLFlow Cytometry 0.5-1 μg/million cells/0.1 mL
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说明
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Human dendritic and mast cells. Human lymph nodes and tonsils.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- CD33
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别名
- CD33
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背景
- Gp67, My9, Myeloid cell surface antigen CD33, p67, Sialic acid-binding Ig-like lectin 3 (SIGLEC3)
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分子量
- 67 kDa
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基因ID
- 945, 83731
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UniProt
- P20138
抗原
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