FSHR 抗体 (CF®647)
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北京 101111
Quick Overview for FSHR 抗体 (CF®647) (ABIN6179512)
抗原
See all FSHR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-FSH Receptor (FSHR/1400), CF647 Conjugate
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产品特性
- Follicle-stimulating hormone receptor (FSHR) is a 695 amino acid G protein coupled receptor. FSH binds to the receptor in a hand-clasp fashion via its ? and ? subunits. While the ? subunit of FSH is involved in the binding of FSH to the receptor, the ? subunit stabilizes this interaction. Linkage studies suggest that a missense mutation in the FSHR gene can cause reduced FSH binding affinity and lead to a condition known as hypergonadotropic ovarian dysgenesis (ODG). In males however, this mutation does not appear to have a detrimental affect on fertility. It is believed that a mutation in the FSHR gene is also associated with ovarian hyperstimulation syndrome, a condition characterized by the presence of multiple serous and hemorrhagic follicular cysts lined by luteinized cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human full-length FSHR protein
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亚型
- IgG1
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anti-Follicle Stimulating Hormone Receptor (FSHR) (AA 201-300) antibody
FSHR 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) (AA 631-695) antibodyFSHR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) (AA 18-366) antibodyFSHR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3D5G9 unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) (AA 21-100) antibodyFSHR 适用: 人, 小鼠, 大鼠 WB, FACS, ICC, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) (AA 18-120) antibodyFSHR 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) (AA 128-140), (Extracellular) antibodyFSHR 适用: 大鼠 WB, IHC, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) (N-Term) antibodyFSHR 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) (N-Term) antibodyFSHR 适用: 人, 大鼠, 猴, 绵羊, Cow, Pig, Bat, 山羊, 马, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) antibodyFSHR 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal FSHR-1400 unconjugated
anti-Follicle Stimulating Hormone Receptor (FSHR) antibodyFSHR 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistology (formalin) 1-2 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA
- pH 9.0
- or 10 mM citrate buffer
- pH 6.0
- for 10-20 min followed by cooling at RT for 20 min
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
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说明
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Uterine Carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- FSHR (Follicle Stimulating Hormone Receptor (FSHR))
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别名
- FSH Receptor
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背景
- Follicle-stimulating hormone receptor, Follitropin receptor, FSH receptor, FSH-R, FSHRO, LGR1, ODG1, ovarian dysgenesis 1
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分子量
- 75 kDa
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基因ID
- 2492, 1428
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UniProt
- P23945
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途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling
抗原
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