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DC-SIGN/CD209 抗体 (CF®594)

This anti-DC-SIGN/CD209 antibody is a 小鼠 单克隆 antibody detecting DC-SIGN/CD209 in FACS, IHC, IF 和 ISt. Suitable for 人.
产品编号 ABIN6179490
发货至: 中国

Quick Overview for DC-SIGN/CD209 抗体 (CF®594) (ABIN6179490)

抗原

See all DC-SIGN/CD209 (CD209) 抗体
DC-SIGN/CD209 (CD209) (CD209)

适用

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宿主

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小鼠

克隆类型

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单克隆

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This DC-SIGN/CD209 antibody is conjugated to CF®594

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunostaining (ISt)

克隆位点

C209-1781
  • 原理

    Mouse Monoclonal anti-CD209 / DC-SIGN (C209/1781), CF594 Conjugate

    产品特性

    DC-SIGN is a transmembrane receptor that is expressed on the surface of dendritic cells and macrophages. It is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens ranging from parasites to viruses. The protein is organized into three distinct domains: an N-terminal transmembrane domain, a tandem-repeat neck domain and C-type lectin carbohydrate recognition domain. The extracellular region consisting of the C-type lectin and neck domains has a dual function as a pathogen recognition receptor and a cell adhesion receptor by binding carbohydrate ligands on the surface of microbes and endogenous cells. The neck region is important for homo-oligomerization, which allows the receptor to bind multivalent ligands with high avidity. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human CD209 protein fragment

    亚型

    IgG2b kappa
  • 应用备注

    Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris with 1 mM EDTA Buffer  pH 9.0for 10-20 min followed by cooling at RT for 20 min
    • Immunohistology (formalin) 0.5 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user

    说明

    THP-1 or HeLa Cells. Small Intestine, Uterus or Lymph Node.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    DC-SIGN/CD209 (CD209) (CD209)

    别名

    CD209 / DC-SIGN

    背景

    CD209, CDSIGN, CIRE, CLEC4L, DC-SIGN, DC-SIGN1, DCSIGN, Dendritic cell-specific ICAM-3 Grabbing Non-integrin 1, HIV GP120 Binding Protein, SIGN-R1, SIGNR5

    分子量

    45 kDa

    基因ID

    30835, 278694

    UniProt

    Q9NNX6
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