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Serotonin Receptor 1A 抗体 (AA 294-312)

This anti-Serotonin Receptor 1A antibody is a 兔 多克隆 antibody detecting Serotonin Receptor 1A in IHC, IF, ICC 和 IEM. Suitable for 人, 大鼠, 小鼠, 猴 和 豚鼠. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN617930
发货至: 中国

Quick Overview for Serotonin Receptor 1A 抗体 (AA 294-312) (ABIN617930)

抗原

See all Serotonin Receptor 1A (HTR1A) 抗体
Serotonin Receptor 1A (HTR1A)

适用

人, 大鼠, 小鼠, 猴, 豚鼠

宿主

  • 43
  • 6
  • 2

克隆类型

  • 46
  • 5
多克隆

标记

  • 25
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Serotonin Receptor 1A antibody is un-conjugated

应用范围

  • 36
  • 17
  • 14
  • 13
  • 13
  • 7
  • 5
  • 4
  • 4
  • 4
  • 1
Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoelectron Microscopy (IEM)
  • 抗原表位

    • 15
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 294-312

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    The 5-HT 1A Receptor Antibody was raised against synthetic peptide sequence corresponding to amino acids 294-312 of the rat 5-HT1A receptor. The antiserum is provided as 100 μL of affinity purified serum containing 1 % BSA. The antiserum demonstrates strongly positive labeling of rat cortex, arcuate and hippocampus using indirect immunofluorescent and biotin/avidin-HRP techniques. Recommended primary dilutions are 1/100 - 1/200 in PBS - Bn/Av-HRP detection. Intensification methods such as nickel will approximately double the dilution factor as recommended. The antibody was characterized by immunohistochemistry and Western blot. Western blot showed a single band of approximately 45 kD. Preincubation of the antibody with an excess of the synthetic peptide blocked staining. Immunohistochemical staining of rat brain correlates well with Northern analysis, in situ hybridization and receptor autoradiography. BlastP database sequence homology searches confirmed that this sequence is unique to rat, mouse and human 5-HT1A receptors.

    纯化方法

    Affinity Purified

    免疫原

    Rat 5-HT1A receptor (294-312)

    亚型

    IgG
  • 限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Contains ≤ 0.09 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    After reconstitution, use immediately or refrigerate at 2 - 8 °C up to 2 days. For long-term storage aliquot antibody and freeze at -15 °C or lower. Avoid repeated freeze/thaw cycles.
  • Lee, Ahn, Won: "New expression of 5-HT1A receptor in astrocytes in the gerbil hippocampal CA1 region following transient global cerebral ischemia." in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, Vol. 36, Issue 3, pp. 383-9, (2016) (PubMed).

    Wang, Wang, Zou, Qu, Liu, Fei, Xia, Needleman, Mikami, Wood: "Mast cell expression of the serotonin1A receptor in guinea pig and human intestine." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 304, Issue 10, pp. G855-63, (2013) (PubMed).

    Ahn, Balaban: "Distribution of 5-HT1B and 5-HT1D receptors in the inner ear." in: Brain research, Vol. 1346, pp. 92-101, (2010) (PubMed).

    Hadjighassem, Austin, Szewczyk, Daigle, Stockmeier, Albert: "Human Freud-2/CC2D1B: a novel repressor of postsynaptic serotonin-1A receptor expression." in: Biological psychiatry, Vol. 66, Issue 3, pp. 214-22, (2009) (PubMed).

    Chalazonitis, Pham, Li, Roman, Guha, Gomes, Kan, Kessler, Gershon: "Bone morphogenetic protein regulation of enteric neuronal phenotypic diversity: relationship to timing of cell cycle exit." in: The Journal of comparative neurology, Vol. 509, Issue 5, pp. 474-92, (2008) (PubMed).

  • 抗原

    Serotonin Receptor 1A (HTR1A)

    背景

    Other Names:
    5-hydroxytryptamine receptor 1A, ADRB2RL1, ADRBRL1,RAT5HT1A, 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

    基因ID

    24473

    途径

    JAK/STAT Signaling, Synaptic Membrane, Feeding Behaviour
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