MCM7 抗体 (AA 195-319) (CF®488A)
Quick Overview for MCM7 抗体 (AA 195-319) (CF®488A) (ABIN6177930)
抗原
See all MCM7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 195-319
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原理
- Mouse Monoclonal anti-MCM7 (MCM7/1467), CF488A Conjugate
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产品特性
- MCM7 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that is essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumor suppressor protein RB1/RB. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human MCM7 protein fragment (aa195-319) (exact sequence is proprietary)
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亚型
- IgG2a kappa
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anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 1-389) antibody
MCM7 适用: 人 WB, IF, ELISA, IHC (p), PLA 宿主: 小鼠 Monoclonal 6C2 unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 360-719) antibodyMCM7 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) antibodyMCM7 适用: 人 WB, IF, IHC (p), IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 526-719) antibodyMCM7 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS, ICC 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (Internal Region) antibodyMCM7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal rMCM7-1468 unconjugated Recombinant Antibody
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 适用: 人 IHC, IF, FACS, StM 宿主: 小鼠 Monoclonal MCM7-1467 unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 适用: 人 WB, IHC, StM 宿主: 兔 Monoclonal MCM7-2832R unconjugated Recombinant Antibody
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 195-319) antibodyMCM7 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal MCM7-1466 unconjugated
anti-Minichromosome Maintenance Complex Component 7 (MCM7) (AA 1-719) antibodyMCM7 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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Immunohistology (formalin) 1-2 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
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说明
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Raji or Ramos cells. Tonsil
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- MCM7 (Minichromosome Maintenance Complex Component 7 (MCM7))
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别名
- MCM7
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背景
- CDC47, DNA replication licensing factor MCM7, MCM7 mini chromosome maintenance deficient 7, Mini chromosome Maintenance 7, Mini chromosome maintenance protein 7, P1.1-MCM3, P1CDC47, P85MCM, PNAS146
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分子量
- 88 kDa
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基因ID
- 4176, 438720
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UniProt
- P33993
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途径
- DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
抗原
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