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CD55 抗体 (CF®640R)

CD55 适用: 人 FACS, IF, IHC (fro) 宿主: 小鼠 Monoclonal 143-30 CF®640R
产品编号 ABIN6177456
发货至: 中国
  • 抗原 See all CD55 抗体
    CD55 (Complement Decay-Accelerating Factor (CD55))
    适用
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    宿主
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    小鼠
    克隆类型
    • 80
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    单克隆
    标记
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    This CD55 antibody is conjugated to CF®640R
    应用范围
    • 98
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    Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    原理
    Mouse Monoclonal anti-CD55 (DAF) (143-30), CF640R Conjugate
    产品特性
    This antibody recognizes a single chain glycoprotein of 70 kDa, identified as CD55 (also known as decay accelerating factor, DAF). CD55/DAF is widely expressed on cells throughout the body including leukocytes, erythrocytes, epithelium, endothelium, and fibroblasts. It is a Glycosyl phosphatidylinositol anchored (GPI-anchored) member of the membrane bound complement regulatory proteins that inhibit autologous complement cascade activation. It prevents the amplification steps of the complement cascade by interfering with the assembly of the C3-convertases, C4b2a and C3bBb, and the C5-convertase, C4b2a3b and C3bBb3b. CD55 also serves as receptor for CD97 and for echovirus and Coxsackie B virus. The MAb 143-30 can be used as marker for paroxysmal nocturnal hemoglobinuria (PNH). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    免疫原
    PHA stimulated human PBL
    克隆位点
    143-30
    亚型
    IgG1 kappa
    Top Product
    Discover our top product CD55 Primary Antibody
  • 应用备注
    Immunohistology (frozen) 0.5-1 μg/mL
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user
    说明

    Jurkat, HUT-78, K562, YT, U937, MG63, and human lymphocytes. Human lymph nodes and tonsils.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100 μg/mL
    缓冲液
    PBS/0.1 % BSA/0.05 % azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Protect from light
  • 抗原
    CD55 (Complement Decay-Accelerating Factor (CD55))
    别名
    CD55 (DAF) (CD55 产品)
    别名
    CR antibody, CROM antibody, DAF antibody, TC antibody, Daf antibody, Daf-GPI antibody, Daf1 antibody, GPI-DAF antibody, CD55 molecule (Cromer blood group) antibody, CD55 molecule, decay accelerating factor for complement antibody, CD55 antibody, Cd55 antibody
    分子量
    70 kDa
    基因ID
    1604, 126517
    UniProt
    P08174
    途径
    Complement System, Regulation of Leukocyte Mediated Immunity
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