CD37 抗体
Quick Overview for CD37 抗体 (ABIN6172623)
抗原
See all CD37 (TSPAN26) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-CD37 (IPO-24), Purified, with BSA
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产品特性
- This antibody recognizes a protein of 33-55 kDa, identified as CD37 (Workshop V, Code CD37.7). CD37 is strongly expressed on normal and neoplastic mature (sIg ) B-lymphocytes. In B-cell ontogeny, CD37 appears after the pre-B-cell stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells.1 CD37 is also present, at low densities, on resting and activated T cells, neutrophils, monocytes, and some myelomonocytic leukemia cells. It is absent from platelets, erythrocytes. CD37 is a member of a family of tetraspan transmembrane proteins, including CD9, CD53, CD63, CD81, and CD82. It associates other tetraspan transmembrane proteins and MHC class II molecules to form a large complex at the surface of B cells and play a role in signal transduction. CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies like B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin'' lymphoma (B-NHL). Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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纯化方法
- Purified
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免疫原
- Spleen cells of a patient with hairy cell leukemia
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亚型
- IgG2b kappa
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anti-Tetraspanin 26 (TSPAN26) (AA 109-237) antibody
TSPAN26 适用: 人 ELISA, IF, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 26 (TSPAN26) antibodyTSPAN26 适用: 人 FACS, IP, IHC (fro) 宿主: 小鼠 Monoclonal MB-1 unconjugated
anti-Tetraspanin 26 (TSPAN26) antibody (PE)TSPAN26 适用: 人 FACS 宿主: 小鼠 Monoclonal MB-1 PE
anti-Tetraspanin 26 (TSPAN26) antibodyTSPAN26 适用: 人 FACS, IF, Func 宿主: 小鼠 Monoclonal IPO-24 unconjugated
anti-Tetraspanin 26 (TSPAN26) antibodyTSPAN26 适用: 人, 小鼠 ELISA, ICC 宿主: 小鼠 Monoclonal 2B8 unconjugated
anti-Tetraspanin 26 (TSPAN26) antibody (PE)TSPAN26 适用: 人 FACS, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4AIPO-24 PE
anti-Tetraspanin 26 (TSPAN26) antibody (FITC)TSPAN26 适用: 人 FACS, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4AIPO-24 FITC
anti-Tetraspanin 26 (TSPAN26) (AA 112-241) antibodyTSPAN26 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM166 unconjugated
anti-Tetraspanin 26 (TSPAN26) (AA 126-175) antibodyTSPAN26 适用: 人, 小鼠, 大鼠, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Tetraspanin 26 (TSPAN26) (AA 91-140) antibodyTSPAN26 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
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说明
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Daudi, Raji, Namalva, Ramos cells and human lymphocytes. Human tonsil and lymph node.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 200 μg/mL
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缓冲液
- PBS/0.05 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- CD37 (TSPAN26) (Tetraspanin 26 (TSPAN26))
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别名
- CD37
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背景
- Cell differentiation antigen 37, GP52 40, Tetraspanin-26, Tspan-26, TSPAN26
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分子量
- 33-55 kDa
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基因ID
- 951, 166556
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UniProt
- P11049
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途径
- Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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