Desmin 抗体 (CF®568)
Quick Overview for Desmin 抗体 (CF®568) (ABIN6171196)
抗原
See all Desmin (DES) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-Desmin (DES/1711), CF568 Conjugate
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产品特性
- Cytoskeletal intermediate filaments (IFs) constitute a diverse group of proteins that are expressed in a highly tissue-specific manner. IFs are constructed from two-chain ?-helical coiled-coil molecules arranged on an imperfect helical lattice, and have been widely used as markers for distinguishing individual cell types within a tissue and identifying the origins of metastatic tumors. Vimentin is an IF general marker of cells originating in the mesenchyme. Vimentin and Desmin, a related class III IF, are both expressed during skeletal muscle development. Desmin, a 469 amino acid protein found near the Z line in sarcomeres, is expressed more frequently in adult differentiated state tissues. Anti-desmin detects cells of normal smooth, skeletal, and cardiac muscles. The antibody reacts with leiomyomas, leiomyosarcoma, rhabdomyomas, rhabdomyosarcoma, and perivascular cells of glomus tumors of the skin. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant human full-length desmin protein
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亚型
- IgG1 kappa
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anti-Desmin (DES) (C-Term) antibody
Verified DES 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Desmin (DES) (AA 1-304) antibodyDES 适用: 人, 大鼠, 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Desmin (DES) (AA 261-360) antibodyDES 适用: 人, 大鼠, 小鼠, 小鸡 WB, ELISA, IHC (p), FACS, IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-Desmin (DES) antibodyDES 适用: 人 WB, IF, IHC (p), FACS, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Desmin (DES) (AA 121-470) antibodyDES 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Desmin (DES) antibodyDES 适用: 人, 大鼠, 小鼠, 小鸡, Hamster, Pig, 犬, 兔, 斑马鱼 WB, IHC, IHC (fro) 宿主: 小鼠 Monoclonal RD301 unconjugated
anti-Desmin (DES) antibodyDES 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 小鼠 Monoclonal 3E1G4 unconjugated
anti-Desmin (DES) (C-Term) antibodyDES 适用: 人, 大鼠, 小鼠 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Desmin (DES) (AA 361-470) antibodyDES 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1D12 unconjugated
anti-Desmin (DES) antibodyDES 适用: 人, 大鼠, 小鼠, Hamster, Pig, 犬, 兔 WB, IHC, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal unconjugated
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应用备注
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Immunohistology (formalin) 1-2 μg/mL
- Immunofluorescence 1-2 μg/mL Flow cytometry 0.5-1 μg/million cells
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
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说明
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SJRH30 Cells. Uterus or Leiomyosarcoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- Desmin (DES)
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别名
- Desmin
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背景
- CMD1I, CSM1, CSM2, DES, Intermediate filament protein
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分子量
- 52 kDa
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基因ID
- 1674, 594952
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UniProt
- P17661
抗原
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