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MMP2 抗体 (AA 444-575) (Biotin)

This anti-MMP2 antibody is a 小鼠 单克隆 antibody detecting MMP2 in WB, IF 和 FACS. Suitable for 人.
产品编号 ABIN6170375
发货至: 中国

Quick Overview for MMP2 抗体 (AA 444-575) (Biotin) (ABIN6170375)

抗原

See all MMP2 抗体
MMP2 (Matrix Metalloproteinase 2 (MMP2))

适用

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宿主

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小鼠

克隆类型

  • 137
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单克隆

标记

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This MMP2 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

MMP2-1501
  • 抗原表位

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    AA 444-575

    原理

    Mouse Monoclonal anti-MMP2 / Collagenase-Type-IV-A (MMP2/1501), Biotin Conjugate

    产品特性

    This antibody recognizes a protein of 72 kDa, which is identified as MMP2. The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-2 (also designated type IV collagenase) cleaves collagen types IV,V, VII and X and gelatin type I. Activation of MMP-2 secretion requires the Ras signaling pathway. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human MMP2 protein fragment (aa444-575) (exact sequence is proprietary)

    亚型

    IgG1
  • 应用备注

    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user

    说明

    U-138 MG or U-87 MG cells. Placenta

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    MMP2 (Matrix Metalloproteinase 2 (MMP2))

    别名

    MMP2 / Collagenase-Type-IV-A

    背景

    72 kD type IV collagenase|CLG4A|Collagenase Type 4 alpha|Collagenase type IV A|Gelatinase A|Gelatinase alpha|Gelatinase neutrophil|Matrix metalloproteinase-2|MMP2|MONA|Neutrophil gelatinase|PEX|TBE-1

    分子量

    72 kDa (Pro), 63 kDa (cleaved)

    基因ID

    4313, 513617

    UniProt

    P08253

    途径

    Activation of Innate immune Response
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