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VLDLR 抗体 (C-Term) (CF®647)

This anti-VLDLR antibody is a 小鼠 单克隆 antibody detecting VLDLR in WB, IHC, FACS, IF 和 ISt. Suitable for 人 和 大鼠.
产品编号 ABIN6168167
发货至: 中国

Quick Overview for VLDLR 抗体 (C-Term) (CF®647) (ABIN6168167)

抗原

See all VLDLR 抗体
VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

适用

  • 80
  • 34
  • 26
  • 6
  • 6
  • 3
  • 3
  • 3
  • 3
人, 大鼠

宿主

  • 66
  • 17
小鼠

克隆类型

  • 54
  • 29
单克隆

标记

  • 30
  • 6
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This VLDLR antibody is conjugated to CF®647

应用范围

  • 55
  • 39
  • 30
  • 24
  • 11
  • 9
  • 4
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunostaining (ISt)

克隆位点

VLDLR-1337
  • 抗原表位

    • 27
    • 16
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    原理

    Mouse Monoclonal anti-VLDL Receptor (VLDLR/1337), CF647 Conjugate

    产品特性

    VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Recombinant human VLDLR fragment from c-terminal (exact sequence is proprietary)

    亚型

    IgG1
  • 应用备注

    Immunohistology (formalin) 1-2 μg/mL
    • Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris, 1 mM EDTA  pH 9.0 for 10-20 min followed by cooling at RT for 20 min
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user

    说明

    HeLa or U-251 cells. Pancreas, Cerebellum, Heart or Skeletal Muscle.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

    别名

    VLDL Receptor

    背景

    Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR

    分子量

    143-161 kDa

    基因ID

    7436

    途径

    Cellular Response to Molecule of Bacterial Origin
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