VLDLR 抗体 (C-Term) (CF®640R)
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- 抗原 See all VLDLR 抗体
- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
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抗原表位
- C-Term
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适用
- 人, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This VLDLR antibody is conjugated to CF®640R
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunostaining (ISt)
- 原理
- Mouse Monoclonal anti-VLDL Receptor (VLDLR/1337), CF640R Conjugate
- 产品特性
- VLDLR (very low density lipoprotein receptor) is a member of the LDL receptor gene family, which includes LDL receptor, LRP, megalin, VLDLR and ApoER2. The LDL receptor family is characterized by a cluster of cysteine-rich class A repeats, epidermal growth factor (EGF)-like repeats, YWTD repeats and an O-linked sugar domain. VLDLR associates with RAP (receptor associated protein) during receptor folding, and RAP facilitates the secretion of the extracellular region of VLDLR. VLDLR is thought to mediate the interaction of extracellular Reelin and cytosolic mDab1 (mammalian disabled protein), which activates a tyrosine kinase. This pathway regulates the migration of neurons along the radial glial fiber network during brain development. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- Recombinant human VLDLR fragment from c-terminal (exact sequence is proprietary)
- 克隆位点
- VLDLR-1337
- 亚型
- IgG1
- Top Product
- Discover our top product VLDLR Primary Antibody
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- 应用备注
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Immunohistology (formalin) 1-2 μg/mL
- Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM Tris, 1 mM EDTA pH 9.0 for 10-20 min followed by cooling at RT for 20 min
- Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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HeLa or U-251 cells. Pancreas, Cerebellum, Heart or Skeletal Muscle.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))
- 别名
- VLDL Receptor (VLDLR 产品)
- 别名
- CARMQ1 antibody, CHRMQ1 antibody, VLDLRCH antibody, AA408956 antibody, AI451093 antibody, AW047288 antibody, vldlr antibody, very low density lipoprotein receptor antibody, very low density lipoprotein receptor S homeolog antibody, VLDLR antibody, Vldlr antibody, vldlr.S antibody
- 背景
- Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR
- 分子量
- 143-161 kDa
- 基因ID
- 7436
- 途径
- Cellular Response to Molecule of Bacterial Origin
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