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CD7 抗体 (APC)

CD7 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-186 APC
产品编号 ABIN616787
发货至: 中国
  • 抗原 See all CD7 抗体
    CD7
    适用
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    宿主
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    小鼠
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    单克隆
    标记
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    This CD7 antibody is conjugated to APC
    应用范围
    • 105
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    Flow Cytometry (FACS)
    特异性
    This antibody reacts with CD7, a 40 kDa type I transmembrane glycoprotein expressed on peripheral blood T lymphocytes, NK-cells, hematopoietic progenitors, monocytes (weakly) and also on acute lymphocytic leukemia.
    交叉反应 (详细)
    Species reactivity (tested):Human
    克隆位点
    MEM-186
    亚型
    IgG1
    Top Product
    Discover our top product CD7 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原
    CD7
    别名
    CD7 (CD7 产品)
    别名
    GP40 antibody, LEU-9 antibody, TP41 antibody, Tp40 antibody, CD7 molecule antibody, CD7 antigen antibody, Cd7 molecule antibody, CD7 antibody, Cd7 antibody
    背景
    CD7, also known as gp40, is a member of the immunoglobulin superfamily found on T cells, NK cells, thymocytes, hematopoietic progenitors, and monocytes (weakly). CD7 is also expressed on acute lymphocytic leukemia (ALL). CD7 crosslinking induces a calcium flux in T lymphocytes, presumably as a result of cytoplasmic domain association with PI3-kinase. CD7 co-stimulation can induce cytokine secretion and modulate cellular adhesion. A ligand of CD7, epithelial cell secreted protein K12, is produced in thymus to regulate thymocyte signaling and cytokine release. In lung microvascular endothelial cells CD7 serves as an IgM Fc receptor. Expression of CD7 is an important marker used in leukemia diagnostics.Synonyms: GP40, Leu-9, T-cell leukemia antigen, TP41
    基因ID
    924
    途径
    Cell-Cell Junction Organization
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