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CD46 抗体 (Biotin)

CD46 适用: 人, Cow FACS 宿主: 小鼠 Monoclonal MEM-258 Biotin
产品编号 ABIN616771
发货至: 中国
  • 抗原 See all CD46 抗体
    CD46
    适用
    • 120
    • 34
    • 20
    • 10
    • 10
    • 3
    人, Cow
    宿主
    • 80
    • 58
    • 2
    小鼠
    克隆类型
    • 70
    • 70
    单克隆
    标记
    • 54
    • 14
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    • 10
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    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
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    This CD46 antibody is conjugated to Biotin
    应用范围
    • 82
    • 81
    • 38
    • 36
    • 28
    • 17
    • 14
    • 14
    • 13
    • 9
    • 6
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    Flow Cytometry (FACS)
    特异性
    This antibody recognizes an epitope on SCR4 (the membrane-proximal SCR) domain of CD46 (Membrane cofactor protein). CD46 is 56-66 kDa dimeric transmembrane protein expressed on T and B lymphocytes, platelets, monocytes, granulocytes, endothelial cells, epithelial cells and fibroblast, it is negative on erythrocytes.
    交叉反应 (详细)
    Species reactivity (tested):Human, Bovine
    免疫原
    HPB-ALL human T cell line
    克隆位点
    MEM-258
    亚型
    IgG1
    Top Product
    Discover our top product CD46 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原
    CD46
    别名
    CD46 / MCP (CD46 产品)
    背景
    CD46 (MCP, membrane cofactor protein) is a multifunctional cell surface transmembrane protein that binds and inactivates C3b and C4b complement fragments, regulates T cell-induced inflammatory responses by either inhibiting (CD46-1 isoform) or increasing (CD46-2 isoform) the contact hypersensitivity reaction. CD46 also serves as a receptor for several human pathogens (both bacteria and viruses), and its ligation alteres T lymphocyte polarization toward antigen-presenting cells or target cells, inhibiting lymphocyte function. CD46 is a protector of placental tissue and is also expressed on the inner acrosomal membrane of spermatozoa.Synonyms: MIC10, Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen
    基因ID
    4179
    NCBI登录号
    NP_002380
    UniProt
    P15529
    途径
    Regulation of Actin Filament Polymerization
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