p40 (p63 Delta) (AA 5-17) 抗体 (CF®488A)
This anti- antibody is a 兔 多克隆 antibody detecting in WB, FACS, IF 和 IHC (f). Suitable for 人, Cow, 小鼠 和 大鼠.
Quick Overview for p40 (p63 Delta) (AA 5-17) 抗体 (CF®488A) (ABIN6167687)
抗原
p40 (p63 Delta)
适用
人, Cow, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
CF®488A
应用范围
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
克隆位点
PAb
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抗原表位
- AA 5-17
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原理
- Rabbit Polyclonal anti-p40 CF488A Conjugate
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产品特性
- p40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p63 antibody's ability to distinguish between the tumor types appears to be inferior when compared to p40. The ability to utilize an antibody probe for p40 as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- A synthetic peptide (ENNAQTQFSEPQY) corresponding to aa5-17 of human p40
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亚型
- IgG
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anti-p40 (p63 Delta) (AA 5-17) antibody
适用: 人, Cow, 小鼠, 大鼠 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistology formalin-fixed 1-2 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
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说明
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HEK293 cells or Prostate Carcinoma or Lung Squamous Cell Carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- p40 (p63 Delta)
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别名
- p40
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背景
- DeltaNp63, TP63
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分子量
- 40 kDa
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基因ID
- 8626, 137569
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UniProt
- Q9H3D4
抗原
-
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