p40 (p63 Delta) (AA 5-17) 抗体 (CF®594)
适用: 人, Cow, 小鼠, 大鼠
WB, FACS, IF, IHC (f)
宿主: 兔
Polyclonal
PAb
CF®594
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- 抗原
- p40 (p63 Delta)
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抗原表位
- AA 5-17
- 适用
- 人, Cow, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- CF®594
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应用范围
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 原理
- Rabbit Polyclonal anti-p40 CF594 Conjugate
- 产品特性
- p40 (p63 delta) is a marker recently determined to be highly specific for squamous basal cells in the immunohistochemistry (IHC) application. The current more routinely recommended marker, p63, appears to have less specificity compared to p40, especially on squamous cell tumors. The ability to differentiate between lung adenocarcinoma vs. squamous cell carcinoma is difficult and has bearing on the different therapeutic avenues for each subtype treatment. p63 antibody's ability to distinguish between the tumor types appears to be inferior when compared to p40. The ability to utilize an antibody probe for p40 as a squamous cell marker bolsters its use for future sub-classification of lung cancers, especially by immunohistochemical techniques. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
- 免疫原
- A synthetic peptide (ENNAQTQFSEPQY) corresponding to aa5-17 of human p40
- 克隆位点
- PAb
- 亚型
- IgG
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anti-p40 (p63 Delta) (AA 5-17) antibody
适用: 人, Cow, 小鼠, 大鼠 WB, FACS, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Immunohistology formalin-fixed 1-2 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Western blotting 0.5-1 μg/mL
- Optimal dilution for a specific application should be determined by user
- 说明
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HEK293 cells or Prostate Carcinoma or Lung Squamous Cell Carcinoma
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100 μg/mL
- 缓冲液
- PBS/0.1 % BSA/0.05 % azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Protect from light
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- 抗原
- p40 (p63 Delta)
- 别名
- p40
- 别名
- AIS antibody, B(p51A) antibody, B(p51B) antibody, EEC3 antibody, KET antibody, LMS antibody, NBP antibody, OFC8 antibody, RHS antibody, SHFM4 antibody, TP53CP antibody, TP53L antibody, TP73L antibody, p40 antibody, p51 antibody, p53CP antibody, p63 antibody, p73H antibody, p73L antibody, tumor protein p63 antibody, TP63 antibody
- 背景
- DeltaNp63, TP63
- 分子量
- 40 kDa
- 基因ID
- 8626, 137569
- UniProt
- Q9H3D4
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