CD72 抗体 (PE)
Quick Overview for CD72 抗体 (PE) (ABIN616763)
抗原
See all CD72 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody reacts with CD72, a 39-43 kDa type II membrane glycoprotein (C-type lectin family). CD72 is a pan-B cell marker expressed throughout the B lymphocytes diferentiation with the exception of plasma cells, it is also present on follicular dendritic cells.
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交叉反应 （详细）
- Species reactivity (tested):Human
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免疫原
- Normal human lymphocytes from a lymph node
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亚型
- IgG2b
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anti-CD72 Molecule (CD72) antibody
CD72 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal 3F3 unconjugated
anti-CD72 Molecule (CD72) (AA 117-359) antibodyCD72 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 4G4B1 unconjugated
anti-CD72 Molecule (CD72) (AA 117-359) antibodyCD72 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2F3B8 unconjugated
anti-CD72 Molecule (CD72) (AA 169-359) antibodyCD72 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD72 Molecule (CD72) (AA 143-345) antibodyCD72 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD72 Molecule (CD72) (AA 126-237) antibodyCD72 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD72 Molecule (CD72) antibodyCD72 适用: 人 FACS, IHC, ELISA, IF, Coat, StM 宿主: 小鼠 Monoclonal BU40 unconjugated
anti-CD72 Molecule (CD72) (AA 4-110) antibodyCD72 适用: 人 FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-CD72 Molecule (CD72) (AA 150-208) antibodyCD72 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-CD72 Molecule (CD72) antibodyCD72 适用: 人 WB, FACS, IP, IHC (fro), IHC (p) 宿主: 小鼠 Monoclonal Bu40 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Dilute only prior to immediate use
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储存条件
- 4 °C
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储存方法
- Store the antibody (undiluted) at 2-8 °C. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.
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- CD72 (CD72 Molecule (CD72))
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别名
- CD72
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背景
- CD72 is a transmembrane glycoprotein expressed as a homodimer especially in B cells, but also in other antigen presenting cells such as dendritic cells and macrophages. Through one of its immunoreceptor tyrosine-based inhibitory motives (ITIMs), CD72 interacts with tyrosine phosphatase SHP-1, thereby suppressing B cell responsiveness. Binding of CD72 with its ligand CD100 (Sema4D) prevents BCR association and phosphorylation of CD72 and results in dissociation of SHP-1 from CD72, thus enables B cell activation.Synonyms: B-Cell marker, B-cell differentiation antigen CD72, Ly-32, Ly32, Lyb-2, Lymphocyte antigen 32
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基因ID
- 971
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NCBI登录号
- NP_001773
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UniProt
- P21854
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途径
- BCR Signaling
抗原
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