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TIMP2 抗体 (N-Term) (Biotin)

This anti-TIMP2 antibody is a 小鼠 单克隆 antibody detecting TIMP2 in WB, IHC, IF 和 FACS. Suitable for 人, 大鼠, 小鼠, Cow, 兔, 斑马鱼 和 豚鼠.
产品编号 ABIN6165490
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for TIMP2 抗体 (N-Term) (Biotin) (ABIN6165490)

抗原

See all TIMP2 抗体
TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

适用

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人, 大鼠, 小鼠, Cow, 兔, 斑马鱼, 豚鼠

宿主

  • 146
  • 56
  • 8
  • 3
  • 1
小鼠

克隆类型

  • 128
  • 86
单克隆

标记

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  • 21
  • 9
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This TIMP2 antibody is conjugated to Biotin

应用范围

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  • 21
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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

3A4
  • 抗原表位

    • 36
    • 35
    • 15
    • 15
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    • 12
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    • 7
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    • 3
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    • 2
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    • 1
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    • 1
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    • 1
    • 1
    • 1
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    • 1
    • 1
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    • 1
    AA 56-66, N-Term

    原理

    Mouse Monoclonal anti-TIMP2 (3A4), Biotin Conjugate

    产品特性

    This antibody recognizes a protein of 21 kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    A synthetic peptide from the N-terminus of human TIMP2 protein (aa56-66) (DSGNDIYGNPI)

    亚型

    IgG2a kappa
  • 应用备注

    Immunohistology (formalin) 1-2 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 min
    • Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Western blotting 0.5-1 μg/mL
    • Optimal dilution for a specific application should be determined by user

    说明

    HeLa cells. Normal Placenta. Breast, Colon, Endometrial, Prostate or Ovarian Carcinoma.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

    别名

    TIMP2

    背景

    Metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, TIMP2, Tissue Inhibitor of Metalloproteinase 2

    分子量

    21 kDa

    基因ID

    7077, 633514

    UniProt

    P16035

    途径

    cAMP Metabolic Process
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