LHCGR 抗体 (N-Term) (CF®488A)
Quick Overview for LHCGR 抗体 (N-Term) (CF®488A) (ABIN6165103)
抗原
See all LHCGR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- N-Term
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原理
- Mouse Monoclonal anti-Luteinizing Hormone / Choriogonadotropin Receptor (LHCGR/1417), CF488A Conjugate
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产品特性
- This antibody recognizes a protein of 78-85 kDa, which is identified as luteinizing hormone/choriogonadotropin receptor. Luteinizing hormone plays a role in spermatogenesis and ovulation by stimulating the testes and ovaries to produce steroids. Choriogonadotropin production in the placenta maintains estrogen and progesterone levels during the first trimester of pregnancy. Ovaries and testes abundantly express luteinizing hormone/choriogonadotropin receptor (LHCGR) as a seven transmembrane, G protein-coupled receptor glycoprotein. LHCGR influences the protective effect of pregnancy and Gonadotropin against breast cancer. The expression of LHCGR on breast carcinoma correlates in part to the degree of tumor differentiation. LHCGR -positive breast tumors occur more frequently in tumors with greater cell differentiation in premenopausal women. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Recombinant N-terminal fragment of human LHCGR (exact sequence is proprietary)
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亚型
- IgG1 kappa
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anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (C-Term) antibody
LHCGR 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) antibodyLHCGR 适用: 人 WB, FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 8G9A2 unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 27-363) antibodyLHCGR 适用: 人 WB, IF, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 201-300) antibodyLHCGR 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 622-699) antibodyLHCGR 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (C-Term) antibodyVerified LHCGR 适用: 人 IF, FACS, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 200-360) antibodyLHCGR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 127-143), (N-Term) antibodyLHCGR 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (C-Term) antibodyLHCGR 适用: 人 WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR) (AA 27-362) antibodyLHCGR 适用: 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistology (formalin) 0.5-1 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 min
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Immunofluorescence 1-2 μg/mL
- Optimal dilution for a specific application should be determined by user
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说明
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HepG2 or Jurkat cells. Ovarian Carcinoma
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
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别名
- Luteinizing Hormone / Choriogonadotropin Receptor
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分子量
- 78-85 kDa
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基因ID
- 3973, 468490
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UniProt
- P22888
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途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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