CD7 抗体 (CF®488A)
Quick Overview for CD7 抗体 (CF®488A) (ABIN6160239)
抗原
See all CD7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Mouse Monoclonal anti-CD7 (B-F12), CF488A Conjugate
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产品特性
- This antibody recognizes a protein of 40 kDa, identified as CD7 (also known as gp40, Leu9). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Chronic Lymphoid Leukemia cells (CLL)
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亚型
- IgG2a kappa
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anti-CD7 (CD7) (AA 26-134) antibody
CD7 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD7 (CD7) (AA 23-128) antibodyCD7 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD7 (CD7) (AA 26-180) antibodyCD7 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 3D11F12 unconjugated
anti-CD7 (CD7) antibodyCD7 适用: 人 FACS, WB, IP, IHC (p) 宿主: 小鼠 Monoclonal MEM-186 unconjugated
anti-CD7 (CD7) antibodyCD7 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-CD7 (CD7) (AA 26-180) antibodyCD7 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2B1C9 unconjugated
anti-CD7 (CD7) (AA 72-175) antibodyCD7 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 5B10E3 unconjugated
anti-CD7 (CD7) (AA 24-150) antibodyCD7 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD7 (CD7) (AA 21-240) antibodyCD7 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1B8 unconjugated
anti-CD7 (CD7) antibodyCD7 适用: 人 IHC 宿主: 兔 Monoclonal MSVA-007R unconjugated Recombinant Antibody
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应用备注
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Immunofluorescence 0.5-1 μg/mL
- Flow Cytometry 0.5-1 μg/million cells/0.1 mL
- Optimal dilution for a specific application should be determined by user
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说明
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Jurkat, HUT-78, Molt-4, CEM cells, or human peripheral blood lymphocytes. Lymph node and tonsil.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- CD7
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别名
- CD7
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背景
- GP40, Leu9, p41, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41
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分子量
- 40 kDa
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基因ID
- 924, 186820
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UniProt
- P09564
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途径
- Cell-Cell Junction Organization
抗原
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