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CD7 抗体 (CF®488A)

This CF®488A-conjugated 小鼠 单克隆 anti-CD7 antibody (Clone 124-1D1) specifically detects CD7 in FACS 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN6160201
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Quick Overview for CD7 抗体 (CF®488A) (ABIN6160201)

抗原

See all CD7 抗体
CD7

适用

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宿主

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小鼠

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单克隆

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This CD7 antibody is conjugated to CF®488A

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

124-1D1
  • 原理

    Mouse Monoclonal anti-CD7 (124.1D1), CF488A Conjugate

    产品特性

    This antibody recognizes a protein of 40 kDa, identified as CD7 (Workshop IV, Code T155). CD7 is a member of the immunoglobulin gene superfamily. Its N-terminal amino acids 1-107 are highly homologous to Ig kappa-L chains whereas the carboxyl-terminal region of the extracellular domain is proline-rich and has been postulated to form a stalk from which the Ig domain projects. CD7 is expressed on the majority of immature and mature T-lymphocytes, and T cell leukemia. It is also found on natural killer cells, a small subpopulation of normal B cells and on malignant B cells. Cross-linking surface CD7 positively modulates T cell and NK cell activity as measured by calcium fluxes, expression of adhesion molecules, cytokine secretion and proliferation. CD7 associates directly with phosphoinositol 3'-kinase. CD7 ligation induces production of D-3 phosphoinositides and tyrosine phosphorylation. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Human leukocytes

    亚型

    IgG1 kappa
  • 应用备注

    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user

    说明

    Jurkat, HUT-78, Molt-4, CEM cells, or human peripheral blood lymphocytes. Lymph node and tonsil.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    CD7

    别名

    CD7

    背景

    GP40, Leu9, p41, T-cell leukemia antigen, T-cell surface antigen Leu-9, Tp40, TP41

    分子量

    40 kDa

    基因ID

    924, 186820

    UniProt

    P09564

    途径

    Cell-Cell Junction Organization
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