HAP1 抗体 (C-Term)
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Quick Overview for HAP1 抗体 (C-Term) (ABIN615992)
抗原
See all HAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-QDAHSKRQQK QK
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特异性
- Recognizes Mouse Hap1
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交叉反应 （详细）
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Species reactivity (expected):Rat.
Species reactivity (tested):Mouse. -
纯化方法
- Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence from the C Terminus of the protein sequence according to NP_034534.1. Genename: Hap1
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anti-Huntingtin Associated Protein 1 (HAP1) (Internal Region) antibody
Verified HAP1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Huntingtin Associated Protein 1 (HAP1) (AA 1-671) antibodyHAP1 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin Associated Protein 1 (HAP1) (AA 132-328) antibodyHAP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin Associated Protein 1 (HAP1) (AA 1-671) antibodyHAP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin Associated Protein 1 (HAP1) (AA 1-671) antibodyHAP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Huntingtin Associated Protein 1 (HAP1) (C-Term) antibodyVerified HAP1 适用: 小鼠, 大鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Huntingtin Associated Protein 1 (HAP1) (AA 328-580) antibodyHAP1 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin Associated Protein 1 (HAP1) (AA 160-381) antibodyHAP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin Associated Protein 1 (HAP1) (Center) antibodyHAP1 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Huntingtin Associated Protein 1 (HAP1) (AA 349-584) antibodyHAP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- HAP1 (Huntingtin Associated Protein 1 (HAP1))
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别名
- HAP1
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背景
- Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. It is a progressive disorder that generally begins in middle age with abnormalities of movement, cognition, personality and mood. HAP-1 is highly expressed in brain and shown to mediate the neuropathology of HD. The human protein interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Two transcripts encoding different isoforms have been identified but one is a nonsense-mediated decay (NMD) candidate.Synonyms: HAP-1, HAP2, HLP1, Huntingtin-associated protein 1, Neuroan 1
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基因ID
- 15114
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NCBI登录号
- NP_034534
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UniProt
- O35668
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途径
- Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Positive Regulation of Response to DNA Damage Stimulus
抗原
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