CD80 抗体 (Internal Region)
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Quick Overview for CD80 抗体 (Internal Region) (ABIN615921)
抗原
See all CD80 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Internal Region
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序列
- C-HLRVNQTFNW NTTK
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特异性
- Recognizes CD80.
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交叉反应 （详细）
- Species reactivity (tested):Human.
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纯化方法
- Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
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免疫原
- Peptide with sequence from the internal region of the protein sequence according to NP_005182.1. Genename: CD80
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anti-CD80 (CD80) (AA 35-244) antibody
CD80 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD80 (CD80) (AA 35-288) antibodyCD80 适用: 人 FACS, ELISA, IHC 宿主: 小鼠 Monoclonal 1G3D7 unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (PerCP)CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 PerCP
anti-CD80 (CD80) (Extracellular Domain) antibody (FITC)CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 FITC
anti-CD80 (CD80) (AA 251-321) antibodyCD80 适用: 人, 小鼠, 大鼠 WB, ELISA, ICC, IHC (p), IHC (fro), IF (p), IF (cc) 宿主: 兔 Polyclonal unconjugated
anti-CD80 (CD80) antibodyCD80 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Monoclonal 3C3 unconjugated Recombinant Antibody
anti-CD80 (CD80) antibodyCD80 适用: 人 ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 2A2 unconjugated
anti-CD80 (CD80) antibodyCD80 适用: 小鼠, 犬 FACS, IP, IHC (fro) 宿主: Armenian Hamster Monoclonal 16-10A1 unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibodyCD80 适用: 人 FACS, IP 宿主: 小鼠 Monoclonal MEM-233 unconjugated
anti-CD80 (CD80) (Extracellular Domain) antibody (APC)CD80 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-233 APC
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD80
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别名
- CD80
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背景
- CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines. Cell Distribution: CD80 is rapidly induced on the surface of activated B cells, T cells and monocytes and is also expressed at high levels on dendritic cells.Synonyms: Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80
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基因ID
- 941
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NCBI登录号
- NP_005182
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UniProt
- P33681
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
抗原
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