XIAP 抗体 (AA 75-226)
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Quick Overview for XIAP 抗体 (AA 75-226) (ABIN615851)
抗原
See all XIAP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 75-226
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特异性
- This antibody reacts to X-linked Inhibitor Of Apoptosis Protein XIAP (XIAP/BIRC4).
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交叉反应 (详细)
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Species reactivity (expected):Mouse (88 %), Rat (90 %), Rabbit (94 %), Pig (92 %).
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography
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免疫原
- Recombinant protein fragment containing a sequence corresponding to a region within amino acids 75 and 226 of BIRC4. Genename: XIAP
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1.0 mg/mL
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缓冲液
- 0.1 M Tris-Glycine, pH 7.0 containing 10 % Glycerol and 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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- XIAP (X-Linked Inhibitor of Apoptosis (XIAP))
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别名
- IAP3 / BIRC4
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背景
- Apoptosis inhibitor 3 (API3) is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. Similar to API1, API3 inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. API3 also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7.Synonyms: API3, Baculoviral IAP repeat-containing protein 4, E3 ubiquitin-protein ligase XIAP, HILP, Inhibitor of apoptosis protein 3, X-linked IAP, X-linked inhibitor of apoptosis protein, XIAP
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基因ID
- 331
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NCBI登录号
- NP_001158
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UniProt
- P98170
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Transition Metal Ion Homeostasis
抗原
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