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NGFR 抗体 (Biotin)

This anti-NGFR antibody is a 小鼠 单克隆 antibody detecting NGFR in FACS, IF 和 IHC (f). Suitable for 人 和 Non-Human Primate.
产品编号 ABIN6158346
发货至: 中国

Quick Overview for NGFR 抗体 (Biotin) (ABIN6158346)

抗原

See all NGFR 抗体
NGFR (Nerve Growth Factor Receptor (NGFR))

适用

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人, Non-Human Primate

宿主

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小鼠

克隆类型

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单克隆

标记

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This NGFR antibody is conjugated to Biotin

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))

克隆位点

NGFR5 NTR-912
  • 原理

    Mouse Monoclonal anti-NGFR (Nerve Growth Factor Receptor) (NGFR5 + NTR/912), Biotin Conjugate

    产品特性

    This antibody recognizes a glycoprotein of 75 kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR). NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    NGFR from A875 melanoma cells (NGFR5), Recombinant human p75 NGFR protein (NTR/912)

    亚型

    IgG
  • 应用备注

    Does not react with mouse or rat, others not known
    • Immunohistology formalin-fixed 0.5-1 μg/mL
    • Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer,  pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Immunofluorescence 1-2 μg/mL
    • Optimal dilution for a specific application should be determined by user

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • 抗原

    NGFR (Nerve Growth Factor Receptor (NGFR))

    别名

    NGFR

    分子量

    75 kDa

    基因ID

    4804

    UniProt

    P08138

    途径

    NF-kappaB Signaling, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis, Growth Factor Binding
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