Plasma Cell Marker 抗体 (CF®647)
This anti- antibody is a 小鼠 单克隆 antibody detecting in IHC (f). Suitable for 人.
Quick Overview for Plasma Cell Marker 抗体 (CF®647) (ABIN6156577)
抗原
Plasma Cell Marker
适用
人
宿主
小鼠
克隆类型
单克隆
标记
CF®647
应用范围
Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
克隆位点
LIV3G11-same as 7B18
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原理
- Mouse Monoclonal anti-Plasma Cell Marker (LIV3G11 (7B18)), CF647 Conjugate
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产品特性
- This antibody recognizes an intra-cytoplasmic antigen, which shows a very high degree of specificity for plasma cells. This antigen is present in normal as well as neoplastic plasma cells. Plasma cells, which are large lymphocytes derived from an antigen-specific B cell, secrete antibodies and are responsible for humoral immunity. Plasma cells differentiate from B cells upon stimulation by CD4 lymphocytes. The B cell acts as an antigen-presenting cell (APC), consuming an offending pathogen, which is taken up by the B cell by phagocytosis and broken down within proteosomes. Plasma cells contain basophilic cytoplasm, their nucleus contains heterochromatin organized in a characteristic cartwheel arrangement. This MAb superbly recognizes normal and neoplastic plasma cells in routine formalin-fixed, paraffin-embedded tissue sections. It is of potential value in identifying myeloma or plasmacytoma in bone marrow or other tissues. It also helps differentiate lympho-plasmacytoid lymphoma from lymphocytic and follicular lymphoma. Note that this MAb is not suitable for staining frozen tissues. Primary antibodies are available purified, or with a selection of fluorescent CF ® dyes and other labels. CF ® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF ®405S and CF ®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
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免疫原
- Pancreatic cancer-related mucin
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亚型
- IgG2a
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anti-Plasma Cell Marker antibody
适用: 人 IHC, StM 宿主: 小鼠 Monoclonal LIV3G11-same as 7B18 unconjugated
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应用备注
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Does not react with rat, others not known
- Immunohistology formalin-fixed 0.1-0.2 μg/mL
- Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes
- Optimal dilution for a specific application should be determined by user
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说明
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Tonsil or lymph node
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100 μg/mL
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缓冲液
- PBS/0.1 % BSA/0.05 % azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Protect from light
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- Plasma Cell Marker
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背景
- Plasma B cell, Plasmocytes
抗原
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