PDE4B 抗体 (C-Term)
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Quick Overview for PDE4B 抗体 (C-Term) (ABIN615425)
抗原
See all PDE4B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- C-DIDIATEDKS PVDT
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特异性
- This antibody detects PDE4B (C-term) and is expected to recognize all reported isoforms.
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交叉反应 (详细)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide from C-terminus of Human PDE4B
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Tris saline buffer, pH ~7.3 containing 0.5 % BSA as stabilizer and 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
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别名
- PDE4B
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背景
- Phosphodiesterase 4B, a cAMP-specific phosphodiesterase, regulates pro-inflammatory and immune cells, and may function in learning, leukemia, memory (or other brain functions), and penile erectile dysfunction. PDE4B activity is inhibited by rolipram. At least three PDE4B isoforms, produced by alternative splicing, have been reported.Synonyms: 5'-cyclic phosphodiesterase 4B, DPDE4, EC=3.1.4.17, PDE32, PDE4B, cAMP-specific 3'
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基因ID
- 5142
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NCBI登录号
- NP_001032416
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UniProt
- Q07343
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途径
- Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
抗原
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