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HLA-DRA 抗体 (CF®568)

This anti-HLA-DRA antibody is a 小鼠 单克隆 antibody detecting HLA-DRA in FACS 和 IF. Suitable for 人, Cow 和 Cat.
产品编号 ABIN6153391
发货至: 中国

Quick Overview for HLA-DRA 抗体 (CF®568) (ABIN6153391)

抗原

See all HLA-DRA 抗体
HLA-DRA (HLA Class II DR alpha (HLA-DRA))

适用

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人, Cow, Cat

宿主

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小鼠

克隆类型

  • 74
  • 73
单克隆

标记

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This HLA-DRA antibody is conjugated to CF®568

应用范围

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Flow Cytometry (FACS), Immunofluorescence (IF)

克隆位点

169-1B5-2
  • 原理

    Mouse Monoclonal anti-MHC-II (HLA-DRA) (169-1B5.2), CF568 Conjugate

    产品特性

    This antibody detects a monomorphic general framework determinant of HLA-DR Class II antigen. It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kDa alpha (heavy) chain and a 28 kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 Molecules, HLA-DR is critical for efficient peptide presentation to CD4 T cells. It is an excellent histiocytic marker in paraffin sections producing intense cytoplasmic staining. True histiocytic neoplasms are similarly positive. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

    免疫原

    Human peripheral blood leukocytes

    亚型

    IgG2b kappa
  • 应用备注

    Immunofluorescence 0.5-1 μg/mL
    • Flow Cytometry 0.5-1 μg/million cells/0.1 mL
    • Optimal dilution for a specific application should be determined by user

    说明

    Ramos, Daudi or HuT78 cells. Tonsil or lymph node

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100 μg/mL

    缓冲液

    PBS/0.1 % BSA/0.05 % azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Protect from light
  • 抗原

    HLA-DRA (HLA Class II DR alpha (HLA-DRA))

    别名

    MHC-II (HLA-DRA)

    分子量

    36 kDa (? chain) and 27 kDa (? chain)

    基因ID

    3122, 520048

    UniProt

    P01903

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
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