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ACE2 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects ACE2 in WB, IHC (p) 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN615244
发货至: 中国
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Quick Overview for ACE2 抗体 (N-Term) (ABIN615244)

抗原

See all ACE2 抗体
ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

适用

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宿主

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克隆类型

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多克隆

标记

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This ACE2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    N-Term

    特异性

    This antibody reacts to Angiotensin I Converting Enzyme 2 (ACE2).

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    ACE2 antibody was raised against synthetic peptide
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store the antibody undiluted at 2-8 °C.
  • 抗原

    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))

    别名

    ACE2

    背景

    Angiotensin-Converting Enzyme 2 (ACE2) plays a central role in vascular, renal, and myocardial physiology. In contrast to its homolog ACE, ACE2 expression is restricted to heart, kidney, and testis. Recently. ACE2 has also been shown to be a functional receptor of the SARS coronavirus. The normal function of ACE2 is to convert the inactive vasoconstrictor angiotensin I (AngI) to Ang1-9 and the active form AngII to Ang1-7, unlike ACE, which converts AngI to AngII. While the role of these vasoactive peptides is not well understood, lack of ACE2 expression in ace2-/ace2- mice leads to severely reduced cardiac contractility, indicating its importance in regulating heart function.Synonyms: ACE-related carboxypeptidase, Angiotensin-converting enzyme 2, Angiotensin-converting enzyme homolog

    基因ID

    59272

    NCBI登录号

    NP_068576

    UniProt

    Q9BYF1

    途径

    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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