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OPTN 抗体 (AA 575-591)

This anti-OPTN antibody is a 兔 多克隆 antibody detecting OPTN in WB 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN615041
发货至: 中国
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Quick Overview for OPTN 抗体 (AA 575-591) (ABIN615041)

抗原

See all OPTN 抗体
OPTN (Optineurin (OPTN))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This OPTN antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 575-591

    特异性

    This antibody reacts to Optineurin (OPTN).

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    OPTN antibody was raised against synthetic peptide corresponding to aa 575-591 (G575EVLPDIDTLQIHVMDC591) of human, mouse and rat optineurin (FIP-2 (14.7K interacting protein-2), NRP (nemo-related protein)). Genename: OPTN
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    TBS, pH 7.4 containing 0.5 mg/mL BSA, 0.02 % sodium azide, 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    OPTN (Optineurin (OPTN))

    别名

    Optineurin / HIP7

    背景

    Optineurin (OTPN), a coiled-coil containing protein, may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.Synonyms: E3-14.7K-interacting protein, FIP-2, FIP2, GLC1E, HYPL, Huntingtin yeast partner L, Huntingtin-interacting protein 7, Huntingtin-interacting protein L, NEMO-related protein, NRP, Optic neuropathy-inducing protein, Transcription factor IIIA-interacting protein

    基因ID

    10133

    NCBI登录号

    NP_001008212

    UniProt

    Q96CV9

    途径

    M Phase
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