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TSC1 抗体 (AA 550-650)

Cited in 1 publication. The 兔 多克隆 anti-TSC1 antibody (ABIN6149609) specifically detects TSC1 in WB, IHC 和 IF. The antibody is reactive with 人 samples.
产品编号 ABIN6149609
发货至: 中国
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Quick Overview for TSC1 抗体 (AA 550-650) (ABIN6149609)

抗原

See all TSC1 抗体
TSC1 (Tuberous Sclerosis 1 (TSC1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TSC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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    AA 550-650

    序列

    QAFTPIDLPC GSADESPAGD RECQTSLETS IFTPSPCKIP PPTRVGFGSG QPPPYDHLFE VALPKTAHHF VIRKTEELLK KAKGNTEEDG VPSTSPMEVL D

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    A synthetic peptide corresponding to a sequence within amino acids 550-650 of human TSC1 (NP_000359.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:1000,IHC,1:50 - 1:100,IF,1:50 - 1:100

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Zheng, Zhou, Zhang, Thu, Xie, Lu, Pang, Xue, Xu, Chen, Chen, Li, Xu: "Anhydroicaritin improves diet-induced obesity and hyperlipidemia and alleviates insulin resistance by suppressing SREBPs activation." in: Biochemical pharmacology, Vol. 122, pp. 42-61, (2017) (PubMed).

  • 抗原

    TSC1 (Tuberous Sclerosis 1 (TSC1))

    别名

    TSC1

    背景

    This gene encodes a growth inhibitory protein thought to play a role in the stabilization of tuberin. Mutations in this gene have been associated with tuberous sclerosis. Alternative splicing results in multiple transcript variants.,TSC1,LAM,TSC,hamartin,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Cancer,Tumor suppressors,Signal Transduction,PI3K-Akt Signaling Pathway,mTOR Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Autophagy,Cell Cycle,Cell cycle inhibitors,Endocrine & Metabolism,AMPK Signaling Pathway,Insulin Receptor Signaling Pathway,Endocrine and metabolic diseases,Obesity,Akt downstream targets,Regulators,TSC1

    分子量

    124 kDa/129 kDa

    基因ID

    7248

    UniProt

    Q92574

    途径

    RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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