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TOP3B 抗体 (AA 1-270)

This anti-TOP3B antibody is a 兔 多克隆 antibody detecting TOP3B in WB. Suitable for 人.
产品编号 ABIN6149394
发货至: 中国

Quick Overview for TOP3B 抗体 (AA 1-270) (ABIN6149394)

抗原

See all TOP3B 抗体
TOP3B (Topoisomerase (DNA) III beta (TOP3B))

适用

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宿主

  • 28
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克隆类型

  • 29
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多克隆

标记

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This TOP3B antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

    • 8
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    AA 1-270

    序列

    MKTVLMVAEK PSLAQSIAKI LSRGSLSSHK GLNGACSVHE YTGTFAGQPV RFKMTSVCGH VMTLDFLGKY NKWDKVDPAE LFSQAPTEKK EANPKLNMVK FLQVEGRGCD YIVLWLDCDK EGENICFEVL DAVLPVMNKA HGGEKTVFRA RFSSITDTDI CNAMACLGEP DHNEALSVDA RQELDLRIGC AFTRFQTKYF QGKYGDLDSS LISFGPCQTP TLGFCVERHD KIQSFKPETY WVLQAKVNTD KDRSLLLDWD RVRVFDREIA

    交叉反应

    人, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human TOP3B (NP_003926.1).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原

    TOP3B (Topoisomerase (DNA) III beta (TOP3B))

    别名

    TOP3B

    背景

    This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Low expression of this gene may be related to higher survival rates in breast cancer patients. This gene has a pseudogene on chromosome 22. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.,TOP3B,TOP3B1,Epigenetics & Nuclear Signaling,RNA Binding,Cancer,Drug resistance,Topoisomerases,TOP3B

    分子量

    79 kDa/82 kDa/96 kDa

    基因ID

    8940

    UniProt

    O95985
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