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TEK 抗体 (AA 500-750)

This anti-TEK antibody is a 兔 多克隆 antibody detecting TEK in WB 和 IHC. Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN6148993
发货至: 中国

Quick Overview for TEK 抗体 (AA 500-750) (ABIN6148993)

抗原

See all TEK 抗体
TEK (TEK Tyrosine Kinase, Endothelial (TEK))

适用

  • 127
  • 64
  • 50
  • 22
  • 4
  • 3

宿主

  • 124
  • 21
  • 4
  • 3
  • 2

克隆类型

  • 130
  • 24
多克隆

标记

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  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
This TEK antibody is un-conjugated

应用范围

  • 86
  • 58
  • 41
  • 40
  • 40
  • 32
  • 24
  • 18
  • 13
  • 12
  • 8
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  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 19
    • 19
    • 16
    • 8
    • 7
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    • 3
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    • 2
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    • 2
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    • 2
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 500-750

    序列

    EIVTLNYLEP RTEYELCVQL VRRGEGGEGH PGPVRRFTTA SIGLPPPRGL NLLPKSQTTL NLTWQPIFPS SEDDFYVEVE RRSVQKSDQQ NIKVPGNLTS VLLNNLHPRE QYVVRARVNT KAQGEWSEDL TAWTLSDILP PQPENIKISN ITHSSAVISW TILDGYSISS ITIRYKVQGK NEDQHVDVKI KNATITQYQL KGLEPETAYQ VDIFAENNIG SSNPAFSHEL VTLPESQAPA DLGGGKMLLI A

    交叉反应

    人, 小鼠, 大鼠

    产品特性

    Polyclonal Antibodies

    免疫原

    Recombinant fusion protein containing a sequence corresponding to amino acids 500-750 of human TEK (NP_000450.2).

    亚型

    IgG
  • 应用备注

    WB,1:500 - 1:2000,IHC,1:50 - 1:100

    说明

    HIGH QUALITY

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Avoid freeze / thaw cycles.
  • Huang, Han, Sun, Zhao, Liu, Yuan, Mao, Peng, Liu, Yin, He: "Kv1.3 channel blocker (ImKTx88) maintains blood-brain barrier in experimental autoimmune encephalomyelitis." in: Cell & bioscience, Vol. 7, pp. 31, (2017) (PubMed).

    Chen, Ren, Zhang, Sun, Wang, Li, Zhang, Zhao: "Disorganized vascular structures in sporadic venous malformations: a possible correlation with balancing effect between Tie2 and TGF-β." in: Scientific reports, Vol. 4, pp. 5457, (2016) (PubMed).

  • 抗原

    TEK (TEK Tyrosine Kinase, Endothelial (TEK))

    别名

    TEK

    背景

    This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known.,TEK,CD202B,GLC3E,TIE-2,TIE2,VMCM,VMCM1,Tie2,Cancer,Signal Transduction,Kinase,Tyrosine kinases,Cell Biology & Developmental Biology,Growth factor,Immunology & Inflammation,CD markers,Stem Cells,Endothelial Progenitors,Cardiovascular,Cardiovascular Markers,Endothelial Cells,Angiogenesis,TEK

    分子量

    109 kDa/121 kDa/125 kDa

    基因ID

    7010

    UniProt

    Q02763

    途径

    RTK signaling, Growth Factor Binding
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