TBC1D23 抗体 (AA 250-600)
Quick Overview for TBC1D23 抗体 (AA 250-600) (ABIN6148882)
抗原
适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 250-600
-
序列
- SDSKEEVIKF LENTPSSLNI EDIEDLFSLA QYYCSKTPAS FRKDNHHLFG STLLGIKDDD ADLSQALCLA ISVSEILQAN QLQGEGVRFF VVDCRPAEQY NAGHLSTAFH LDSDLMLQNP SEFAQSVKSL LEAQKQSIES GSIAGGEHLC FMGSGREEED MYMNMVLAHF LQKNKEYVSI ASGGFMALQQ HLADINVDGP ENGYGHWIAS TSGSRSSINS VDGESPNGSS DRGMKSLVNK MTVALKTKSV NVREKVISFI ENTSTPVDRM SFNLPWPDRS CTERHVSSSD RVGKPYRGVK PVFSIGDEEE YDTDEIDSSS MSDDDRKEVV NIQTWINKPD VKHHFPCKEV K
-
交叉反应
- 人, 小鼠
-
产品特性
- Polyclonal Antibodies
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 250-600 of human TBC1D23 (NP_001186127.1).
-
亚型
- IgG
-
-
anti-TBC1 Domain Family, Member 23 (TBC1D23) (Internal Region) antibody
TBC1D23 适用: 人, 小鼠, 大鼠 WB, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 23 (TBC1D23) (AA 510-605) antibodyTBC1D23 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-TBC1 Domain Family, Member 23 (TBC1D23) (C-Term) antibodyTBC1D23 适用: 人, 小鼠, 大鼠, 豚鼠, Cow, 犬, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB,1:500 - 1:2000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
-
别名
- TBC1D23
-
背景
- Putative Rab GTPase-activating protein which plays a role in vesicular trafficking. Involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. Plays a role in brain development, including in cortical neuron positioning (By similarity. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth (By similarity. May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS challenge (By similarity.,TBC1D23,NS4ATP1,TBC1D23
-
分子量
- 76 kDa/78 kDa
-
基因ID
- 55773
-
UniProt
- Q9NUY8
抗原
-
