APOC1 抗体
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Quick Overview for APOC1 抗体 (ABIN614885)
抗原
See all APOC1 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody recognizes human Apo C-I in plasma and lipoproteins. Does not cross-react with plasma Apo A-I, Apo A-II, Apo B-100, Apo C-II, Apo C-III and Apo-E.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Immunoaffinity chromatography
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免疫原
- Native human Apo C-I Genename: APOC1
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS, pH 7.2, 0.5 mM EDTA, 0.02 % sodium azide, 40 % glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- APOC1 (Apolipoprotein C-I (APOC1))
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别名
- Apolipoprotein C I (Apo CI)
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背景
- Apolipoprotein (apo) C-I gene is expressed primarily in the liver, and it is activated when monocytes differentiate into macrophages. A copy of the apo C-I gene, apo C-I', is located 4 kb downstream in the same orientation, on the same chromosome. However, apo C-I' gene has no detectable mRNA product in any tissue, suggesting that it may be a pseudogene. The ap °C-I gene is 4653 bases long and the apo C-I' is 4387 base pairs, and each contains four exons and 3 introns. The differences between the two genes includes a change of the codon for Gln-2 of the signal peptide region of apo C-I', which introduces a translation stop signal. A major difference between the two sequences is also found in the second and third introns of the ap °C-I' gene, which contains 7.5 instead of 9 copies of Alu family sequences.Synonyms: Apo-CI, Ap °C-I, Ap °C1, Apolipoprotein C-I, Apolipoprotein C1
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基因ID
- 341
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NCBI登录号
- NP_001636
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UniProt
- P02654
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途径
- Apoptosis
抗原
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