TAB2 抗体 (AA 350-693)
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北京 101111
Quick Overview for TAB2 抗体 (AA 350-693) (ABIN6148797)
抗原
See all TAB2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 350-693
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序列
- STSSSVNSQT LNRNQPTVYI AASPPNTDEL MSRSQPKVYI SANAATGDEQ VMRNQPTLFI STNSGASAAS RNMSGQVSMG PAFIHHHPPK SRAIGNNSAT SPRVVVTQPN TKYTFKITVS PNKPPAVSPG VVSPTFELTN LLNHPDHYVE TENIQHLTDP TLAHVDRISE TRKLSMGSDD AAYTQALLVH QKARMERLQR ELEIQKKKLD KLKSEVNEME NNLTRRRLKR SNSISQIPSL EEMQQLRSCN RQLQIDIDCL TKEIDLFQAR GPHFNPSAIH NFYDNIGFVG PVPPKPKDQR SIIKTPKTQD TEDDEGAQWN CTACTFLNHP ALIRCEQCEM PRHF
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 350-693 of human TAB2 (NP_001278963.1).
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亚型
- IgG
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anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (N-Term) antibody
TAB2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (N-Term) antibodyTAB2 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Pig, Bat, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) antibodyTAB2 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) antibodyTAB2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3B5 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 646-680), (C-Term) antibodyTAB2 适用: 大鼠 WB 宿主: 兔 Polyclonal RB52974 unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (Internal Region) antibodyTAB2 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 1-693) antibodyTAB2 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2) (AA 1-693) antibodyTAB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
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别名
- TAB2
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背景
- The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, and it thus serves as an adaptor that links MAP3K7 and TRAF6. This protein, along with TAB1 and MAP3K7, also participates in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappaB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Studies of the related mouse protein indicate that it functions to protect against liver damage caused by chemical stressors. Mutations in this gene cause congenital heart defects, multiple types, 2 (CHTD2). Alternative splicing results in multiple transcript variants.,TAB2,CHTD2,MAP3K7IP2,TAB-2,Signal Transduction,Kinase,ErbB-HER Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Inhibition of Apoptosis,Wnt/β-Catenin Signaling Pathway,Immunology & Inflammation,NF-kB Signaling Pathway,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,TAB2
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分子量
- 58 kDa/76 kDa
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基因ID
- 23118
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UniProt
- Q9NYJ8
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途径
- TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
抗原
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