STRAP 抗体 (AA 1-350)
Quick Overview for STRAP 抗体 (AA 1-350) (ABIN6148639)
抗原
See all STRAP 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-350
-
序列
- MAMRQTPLTC SGHTRPVVDL AFSGITPYGY FLISACKDGK PMLRQGDTGD WIGTFLGHKG AVWGATLNKD ATKAATAAAD FTAKVWDAVS GDELMTLAHK HIVKTVDFTQ DSNYLLTGGQ DKLLRIYDLN KPEAEPKEIS GHTSGIKKAL WCSEDKQILS ADDKTVRLWD HATMTEVKSL NFNMSVSSME YIPEGEILVI TYGRSIAFHS AVSLDPIKSF EAPATINSAS LHPEKEFLVA GGEDFKLYKY DYNSGEELES YKGHFGPIHC VRFSPDGELY ASGSEDGTLR LWQTVVGKTY GLWKCVLPEE DSGELAKPKI GFPETTEEEL EEIASENSDC IFPSAPDVKA
-
交叉反应
- 人, 小鼠, 大鼠
-
产品特性
- Polyclonal Antibodies
-
免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-350 of human STRAP (NP_009109.3).
-
亚型
- IgG
-
-
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 1-350) antibody
STRAP 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (N-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 242-269), (C-Term) antibodySTRAP 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20860 unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (N-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 101-150) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 斑马鱼, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (C-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) antibodySTRAP 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 281-330) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (AA 78-104), (N-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Serine/threonine Kinase Receptor Associated Protein (STRAP) (C-Term) antibodySTRAP 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB,1:1000 - 1:2000,IF,1:50 - 1:200,IP,1:50 - 1:200
-
说明
-
HIGH QUALITY
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- STRAP (Serine/threonine Kinase Receptor Associated Protein (STRAP))
-
别名
- STRAP
-
背景
- The SMN complex catalyzes the assembly of small nuclear ribonucleoproteins (snRNPs, the building blocks of the spliceosome, and thereby plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in a heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP (Sm core. In the cytosol, the Sm proteins SNRPD1, SNRPD2, SNRPE, SNRPF and SNRPG are trapped in an inactive 6S pICln-Sm complex by the chaperone CLNS1A that controls the assembly of the core snRNP. To assemble core snRNPs, the SMN complex accepts the trapped 5Sm proteins from CLNS1A forming an intermediate. Binding of snRNA inside 5Sm triggers eviction of the SMN complex, thereby allowing binding of SNRPD3 and SNRPB to complete assembly of the core snRNP. STRAP plays a role in the cellular distribution of the SMN complex. Negatively regulates TGF-beta signaling but positively regulates the PDPK1 kinase activity by enhancing its autophosphorylation and by significantly reducing the association of PDPK1 with 14-3-3 protein.,STRAP,MAWD,PT-WD,UNRIP,Epigenetics & Nuclear Signaling,RNA Binding,Signal Transduction,Kinase,STRAP
-
分子量
- 38 kDa/39 kDa
-
基因ID
- 11171
-
UniProt
- Q9Y3F4
抗原
-
