Ubinuclein 1 抗体 (N-Term)
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Quick Overview for Ubinuclein 1 抗体 (N-Term) (ABIN614815)
抗原
See all Ubinuclein 1 (UBN1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-190, N-Term
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特异性
- This antibody recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Protein-A affinity chromatography
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纯度
- > 95 % pure by SDS-PAGE
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免疫原
- Recombinant protein corresponding to amino acids 1-190 of ubinuclein 1
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Ubinuclein 1 (UBN1)
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别名
- Ubinuclein-1 (UBN1)
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背景
- Ubinuclein 1 (UBN1) is a ubiquitously expressed evolutionarily conserved protein which binds to proliferation-promoting genes that are repressed by formation of senescence-associated heterochromatin foci (SAHF). Ubinuclein 1 associates with various transcription factors and with histone methyltransferase activity, is indispensable for SAHF formation and appears to be a regulator of senescence. Although in most cells ubinuclein is localized to the nucleus, in cells forming tight junctions it is recruited to the cell adhesion complexes, dependently on the cell density.Synonyms: HIRA-binding protein, Protein VT4, Ubiquitously expressed nuclear protein
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基因ID
- 29855
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NCBI登录号
- NP_058632
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UniProt
- Q9NPG3
抗原
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