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Ubinuclein 1 抗体 (N-Term)

This anti-Ubinuclein 1 antibody is a 小鼠 单克隆 antibody detecting Ubinuclein 1 in WB 和 IP. Suitable for 人.
产品编号 ABIN614815
发货至: 中国

Quick Overview for Ubinuclein 1 抗体 (N-Term) (ABIN614815)

抗原

See all Ubinuclein 1 (UBN1) 抗体
Ubinuclein 1 (UBN1)

适用

  • 24
  • 8
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1

宿主

  • 19
  • 4
  • 1
小鼠

克隆类型

  • 20
  • 4
单克隆

标记

  • 17
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Ubinuclein 1 antibody is un-conjugated

应用范围

  • 12
  • 8
  • 6
  • 3
  • 3
  • 1
Western Blotting (WB), Immunoprecipitation (IP)

克隆位点

UBN1-02
  • 抗原表位

    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-190, N-Term

    特异性

    This antibody recognizes N-terminal part of ubinuclein 1 (UBN1), a widely expressed nuclear and adhesion complex protein. Western blotting analysis reveals UBN1 as a 165 kDa band.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein-A affinity chromatography

    纯度

    > 95 % pure by SDS-PAGE

    免疫原

    Recombinant protein corresponding to amino acids 1-190 of ubinuclein 1

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Ubinuclein 1 (UBN1)

    别名

    Ubinuclein-1 (UBN1)

    背景

    Ubinuclein 1 (UBN1) is a ubiquitously expressed evolutionarily conserved protein which binds to proliferation-promoting genes that are repressed by formation of senescence-associated heterochromatin foci (SAHF). Ubinuclein 1 associates with various transcription factors and with histone methyltransferase activity, is indispensable for SAHF formation and appears to be a regulator of senescence. Although in most cells ubinuclein is localized to the nucleus, in cells forming tight junctions it is recruited to the cell adhesion complexes, dependently on the cell density.Synonyms: HIRA-binding protein, Protein VT4, Ubiquitously expressed nuclear protein

    基因ID

    29855

    NCBI登录号

    NP_058632

    UniProt

    Q9NPG3
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