Ubinuclein 1 抗体 (AA 161-210)
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Quick Overview for Ubinuclein 1 抗体 (AA 161-210) (ABIN1534139)
抗原
See all Ubinuclein 1 (UBN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-210
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原理
- UBN-1 Antibody
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特异性
- UBN-1 Polyclonal Antibody detects endogenous levels of UBN-1 protein.
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纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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纯度
- > 95 %
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免疫原
- The antiserum was produced against synthesized peptide derived from human Ubinuclein. AA range:161-210
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亚型
- IgG
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anti-Ubinuclein 1 (UBN1) antibody
UBN1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubinuclein 1 (UBN1) (AA 1-345) antibodyUBN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubinuclein 1 (UBN1) (Internal Region) antibodyVerified UBN1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Ubinuclein 1 (UBN1) (AA 974-1023) antibodyUBN1 适用: 人, Cow, 犬, 豚鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubinuclein 1 (UBN1) (C-Term) antibodyUBN1 适用: 人, 小鼠, 大鼠, Cow, 犬 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubinuclein 1 (UBN1) antibodyUBN1 适用: 人 DB 宿主: 小鼠 Monoclonal UBN1G12 unconjugated
anti-Ubinuclein 1 (UBN1) (Internal Region) antibodyUBN1 适用: 人, 小鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ubinuclein 1 (UBN1) (AA 1084-1134) antibodyUBN1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubinuclein 1 (UBN1) (AA 1-190) antibodyUBN1 适用: 人 WB, IP 宿主: 小鼠 Monoclonal UBN1-02 unconjugated
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应用备注
- WB 1:500-2000 IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C/1 year
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有效期
- 12 months
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- Ubinuclein 1 (UBN1)
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背景
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Synonyms: UBN1, Ubinuclein-1, HIRA-binding protein, Protein VT4, Ubiquitously expressed nuclear protein
Background: function:Acts as a novel regulator of senescence. Involved in the formation of senescence-associated heterochromatin foci (SAHF), which represses expression of proliferation-promoting genes. Binds to proliferation-promoting genes. May be required for replication-independent chromatin assembly.,similarity:Belongs to the ubinuclein family.,subcellular location:Localized as a nuclear speckled-like pattern in proliferating primary fibroblasts. Colocalizes with HIRA, PML and SP100 in PML bodies of senescent cells. Colocalizes with TJP1 and CLDN1. Detected along the upper granular cell layer of epidermis. When overexpressed, accumulates in the nucleus in cells showing defective cytokinesis.,subunit:Component of a complex that includes at least ASF1A, CABIN1, HIRA, histone H3.3 and UBN1. Interacts with Epstein-Barr virus BZLF1. Interacts with HIRA (via WD repeat domain), the interaction is direct. Interacts with ASF1A, CEBPA, TJP1, TJP2 and TJP3.,tissue specificity:Ubiquitous. Also expressed in numerous tumors and cancer cell lines.,
Gene Name: UBN1
Protein Name: Ubinuclein-1
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分子量
- 121 kDa
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基因ID
- 29855
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OMIM
- 609771
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UniProt
- Q9NPG3
抗原
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