SMPD3 抗体 (AA 416-655)
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北京 101111
Quick Overview for SMPD3 抗体 (AA 416-655) (ABIN6148146)
抗原
See all SMPD3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 416-655
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序列
- MDVAYHCYPN KCNDDALASK GALFLKVQVG STPQDQRIVG YIACTHLHAP QEDSAIRCGQ LDLLQDWLAD FRKSTSSSSA ANPEELVAFD VVCGDFNFDN CSSDDKLEQQ HSLFTHYRDP CRLGPGEEKP WAIGTLLDTN GLYDEDVCTP DNLQKVLESE EGRREYLAFP TSKSSGQKGR KELLKGNGRR IDYMLHAEEG LCPDWKAEVE EFSFITQLSG LTDHLPVAMR LMVSSGEEEA
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 416-655 of human SMPD3 (NP_061137.1).
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亚型
- IgG
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anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 1-655) antibody
SMPD3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 401-655) antibodySMPD3 适用: 人 ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (Middle Region) antibodySMPD3 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 1-655) antibodySMPD3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) antibodySMPD3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:1000 - 1:3000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))
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别名
- SMPD3
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背景
- Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Regulates the cell cycle by acting as a growth suppressor in confluent cells. Probably acts as a regulator of postnatal development and participates in bone and dentin mineralization. Binds to anionic phospholipids (APLs such as phosphatidylserine (PS and phosphatidic acid (PA that modulate enzymatic activity and subcellular location. May be involved in IL-1-beta-induced JNK activation in hepatocytes (By similarity. May act as a mediator in transcriptional regulation of NOS2/iNOS via the NF-kappa-B activation under inflammatory conditions (By similarity.,SMPD3,NSMASE2,Cell Biology & Developmental Biology,Apoptosis,Neuroscience,Cell Type Marker,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Oligodendrocyte marker,Neuron marker,SMPD3
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分子量
- 70 kDa/71 kDa
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基因ID
- 55512
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UniProt
- Q9NY59
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途径
- Hormone Transport
抗原
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