SMPD3 抗体 (Middle Region)
(1 reference)-
- 抗原 See all SMPD3 抗体
- SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))
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抗原表位
- Middle Region
- 适用
- 人, 小鼠, 大鼠, 兔, Cow, 犬, 豚鼠, 马
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMPD3 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- RPPEADDPVP GGQARNGAGG GPRGQTPNHN QQDGDSGSLG SPSASRESLV
- 预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
- 产品特性
- This is a rabbit polyclonal antibody against SMPD3. It was validated on Western Blot using a cell lysate as a positive control.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human SMPD3
- Top Product
- Discover our top product SMPD3 Primary Antibody
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anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 1-655) antibody
SMPD3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 401-655) antibodySMPD3 适用: 人 ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 1-655) antibodySMPD3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) (AA 416-655) antibodySMPD3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sphingomyelin Phosphodiesterase 3 (SMPD3) antibodySMPD3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
- 说明
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Antigen size: 655 AA
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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: "Analysis of membrane topology of neutral sphingomyelinase 2." in: FEBS letters, Vol. 581, Issue 7, pp. 1323-8, (2007) (PubMed).
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: "Analysis of membrane topology of neutral sphingomyelinase 2." in: FEBS letters, Vol. 581, Issue 7, pp. 1323-8, (2007) (PubMed).
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- 抗原
- SMPD3 (Sphingomyelin Phosphodiesterase 3 (SMPD3))
- 别名
- SMPD3 (SMPD3 产品)
- 别名
- 4631433G07Rik antibody, AI427456 antibody, AW537966 antibody, fro antibody, nSMase2 antibody, cca1 antibody, NSMASE2 antibody, sphingomyelin phosphodiesterase 3 antibody, sphingomyelin phosphodiesterase 3, neutral antibody, SMPD3 antibody, Smpd3 antibody
- 背景
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SMPD3 catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. SMPD3 regulates the cell cycle by acting as a growth suppressor in confluent cells. It probably acts as a regulator of postnatal development and participates in bone and dentin mineralization.
Alias Symbols: FLJ22593, MGC138443, NSMASE2
Protein Size: 655 - 分子量
- 71 kDa
- 基因ID
- 55512
- NCBI登录号
- NM_018667, NP_061137
- UniProt
- Q9NY59
- 途径
- Hormone Transport
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